Literature DB >> 31764652

Outcomes, Challenges, and Pitfalls after Targeted Muscle Reinnervation in High-Level Amputees: Is It Worth the Effort?

Stefan Salminger1, Agnes Sturma, Aidan D Roche, Johannes A Mayer, Clemens Gstoettner, Oskar C Aszmann.   

Abstract

BACKGROUND: Although the distal targets have been lost in proximal upper limb amputees, the neural signals for intuitive hand and arm function are still available and thus can be incorporated into more useful prosthetic function using targeted muscle reinnervation technique. In this article, the authors present their outcomes and range of indications in addition to experiences and pitfalls after 30 targeted muscle reinnervation cases at above-elbow and shoulder disarticulation level of amputation.
METHODS: Thirty patients with above-elbow or shoulder disarticulation amputations were enrolled between 2012 and 2017. Indications for targeted muscle reinnervation surgery differed between improvement of prosthetic function (n = 19) and/or pain (n = 11). Functional outcome was evaluated with the Action Research Arm Test, the Southampton Hand Assessment Procedure, and the Clothespin-Relocation Test. Functional evaluation was performed at least at 6 months after final prosthetic fitting.
RESULTS: All nerve transfers were successful and provided independent myoelectric signals. The 10 patients available for final functional evaluation showed Action Research Arm Test scores of 20.4 ± 1.9 and Southampton Hand Assessment Procedure scores of 40.5 ± 8.1. The Clothespin-Relocation Test showed a mean time of 34.3 ± 14.4 seconds.
CONCLUSIONS: Targeted muscle reinnervation has improved prosthetic control and revolutionized neuroma treatment in upper limb amputees. Still, the rate of abandonment even after targeted muscle reinnervation surgery has been shown high, and several advances within the biotechnological interface will be needed to improve prosthetic function and acceptance in these patients. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

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Year:  2019        PMID: 31764652     DOI: 10.1097/PRS.0000000000006277

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  7 in total

1.  MUW researcher of the month.

Authors:  Stefan Salminger
Journal:  Wien Klin Wochenschr       Date:  2020-09       Impact factor: 1.704

2.  Variation on a technique for the intra-muscular insertion of nerve endings to minimise neuropathic and residual pain in lower limb amputees: a retrospective cohort study.

Authors:  Victor Lu; Andrew Zhou; Matija Krkovic
Journal:  Eur J Orthop Surg Traumatol       Date:  2022-05-25

3.  Feasibility of a Wireless Implantable Multi-electrode System for High-bandwidth Prosthetic Interfacing: Animal and Cadaver Study.

Authors:  Clemens Gstoettner; Christopher Festin; Cosima Prahm; Konstantin D Bergmeister; Stefan Salminger; Agnes Sturma; Christian Hofer; Michael F Russold; Charla L Howard; Daniel McDonnall; Dario Farina; Oskar C Aszmann
Journal:  Clin Orthop Relat Res       Date:  2022-02-23       Impact factor: 4.755

Review 4.  Target Receptors of Regenerating Nerves: Neuroma Formation and Current Treatment Options.

Authors:  Feras Shamoun; Valentina Shamoun; Arya Akhavan; Sami H Tuffaha
Journal:  Front Mol Neurosci       Date:  2022-07-05       Impact factor: 6.261

Review 5.  [Surgical management of peripheral nerves after extremity loss].

Authors:  Clemens Gstoettner; Gregor Laengle; Stefan Salminger; Christopher Festin; Hannes Platzgummer; Oskar C Aszmann
Journal:  Orthopade       Date:  2021-01       Impact factor: 1.087

6.  Targeted Muscle Reinnervation and the Volar Forearm Filet Flap for Forequarter Amputation: Description of Operative Technique.

Authors:  Marie T Morris; Christopher J Dy; Martin I Boyer; David M Brogan
Journal:  J Hand Surg Glob Online       Date:  2020-07-09

7.  Bionic Upper Limb Reconstruction: A Valuable Alternative in Global Brachial Plexus Avulsion Injuries-A Case Series.

Authors:  Laura A Hruby; Clemens Gstoettner; Agnes Sturma; Stefan Salminger; Johannes A Mayer; Oskar C Aszmann
Journal:  J Clin Med       Date:  2019-12-20       Impact factor: 4.241

  7 in total

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