Literature DB >> 31762428

Antimicrobial-resistant pathogens associated with pediatric healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015-2017.

Lindsey M Weiner-Lastinger1, Sheila Abner1, Andrea L Benin1, Jonathan R Edwards1, Alexander J Kallen1, Maria Karlsson1, Shelley S Magill1, Daniel Pollock1, Isaac See1, Minn M Soe1, Maroya S Walters1, Margaret A Dudeck1.   

Abstract

OBJECTIVE: To describe common pathogens and antimicrobial resistance patterns for healthcare-associated infections (HAIs) among pediatric patients that occurred in 2015-2017 and were reported to the Centers for Disease Control and Prevention's National Healthcare Safety Network (NHSN).
METHODS: Antimicrobial resistance data were analyzed for pathogens implicated in central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs), ventilator-associated pneumonias (VAPs), and surgical site infections (SSIs). This analysis was restricted to device-associated HAIs reported from pediatric patient care locations and SSIs among patients <18 years old. Percentages of pathogens with nonsusceptibility (%NS) to selected antimicrobials were calculated by HAI type, location type, and surgical category.
RESULTS: Overall, 2,545 facilities performed surveillance of pediatric HAIs in the NHSN during this period. Staphylococcus aureus (15%), Escherichia coli (12%), and coagulase-negative staphylococci (12%) were the 3 most commonly reported pathogens associated with pediatric HAIs. Pathogens and the %NS varied by HAI type, location type, and/or surgical category. Among CLABSIs, the %NS was generally lowest in neonatal intensive care units and highest in pediatric oncology units. Staphylococcus spp were particularly common among orthopedic, neurosurgical, and cardiac SSIs; however, E. coli was more common in abdominal SSIs. Overall, antimicrobial nonsusceptibility was less prevalent in pediatric HAIs than in adult HAIs.
CONCLUSION: This report provides an updated national summary of pathogen distributions and antimicrobial resistance patterns among pediatric HAIs. These data highlight the need for continued antimicrobial resistance tracking among pediatric patients and should encourage the pediatric healthcare community to use such data when establishing policies for infection prevention and antimicrobial stewardship.

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Year:  2019        PMID: 31762428      PMCID: PMC8276251          DOI: 10.1017/ice.2019.297

Source DB:  PubMed          Journal:  Infect Control Hosp Epidemiol        ISSN: 0899-823X            Impact factor:   3.254


  8 in total

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2.  Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015-2017.

Authors:  Lindsey M Weiner-Lastinger; Sheila Abner; Jonathan R Edwards; Alexander J Kallen; Maria Karlsson; Shelley S Magill; Daniel Pollock; Isaac See; Minn M Soe; Maroya S Walters; Margaret A Dudeck
Journal:  Infect Control Hosp Epidemiol       Date:  2019-11-26       Impact factor: 3.254

3.  Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance.

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7.  Pathogen Distribution and Antimicrobial Resistance Among Pediatric Healthcare-Associated Infections Reported to the National Healthcare Safety Network, 2011-2014.

Authors:  Jason G Lake; Lindsey M Weiner; Aaron M Milstone; Lisa Saiman; Shelley S Magill; Isaac See
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  8 in total
  19 in total

1.  Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015-2017.

Authors:  Lindsey M Weiner-Lastinger; Sheila Abner; Jonathan R Edwards; Alexander J Kallen; Maria Karlsson; Shelley S Magill; Daniel Pollock; Isaac See; Minn M Soe; Maroya S Walters; Margaret A Dudeck
Journal:  Infect Control Hosp Epidemiol       Date:  2019-11-26       Impact factor: 3.254

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