Literature DB >> 31762277

(-)- and (+)-Asperginulin A, a Pair of Indole Diketopiperazine Alkaloid Dimers with a 6/5/4/5/6 Pentacyclic Skeleton from the Mangrove Endophytic Fungus Aspergillus sp. SK-28.

Runlin Cai1, Hongming Jiang1, Zeen Xiao1, Wenhao Cao2, Tao Yan2, Zhaoming Liu1, Shao'e Lin1, Yuhua Long3, Zhigang She1,4.   

Abstract

A pair of enantiomeric indole diketopiperazine alkaloid dimers [(-)- and (+)-asperginulin A (1a and 1b)] with an unprecedented 6/5/4/5/6 pentacyclic skeleton were isolated from the mangrove endophytic fungus Aspergillus sp. SK-28. The enantiomeric dimers were separated by chiral-phase HPLC. Their structures including absolute configurations were elucidated by spectroscopic analysis, X-ray diffraction, and quantum chemical calculation. (+)-Asperginulin A (1b) exhibited antifouling activity against the barnacle Balanus reticulatus.

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Year:  2019        PMID: 31762277     DOI: 10.1021/acs.orglett.9b03796

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  10 in total

Review 1.  Natural Enantiomers: Occurrence, Biogenesis and Biological Properties.

Authors:  Jin-Hai Yu; Zhi-Pu Yu; Robert J Capon; Hua Zhang
Journal:  Molecules       Date:  2022-02-14       Impact factor: 4.411

2.  Two Antimicrobial Heterodimeric Tetrahydroxanthones with a 7,7'-Linkage from Mangrove Endophytic Fungus Aspergillus flavus QQYZ.

Authors:  Zhenming Zang; Wencong Yang; Hui Cui; Runlin Cai; Chunyuan Li; Ge Zou; Bo Wang; Zhigang She
Journal:  Molecules       Date:  2022-04-22       Impact factor: 4.927

Review 3.  Structures and Biological Activities of Diketopiperazines from Marine Organisms: A Review.

Authors:  Zhiqiang Song; Yage Hou; Qingrong Yang; Xinpeng Li; Shaohua Wu
Journal:  Mar Drugs       Date:  2021-07-21       Impact factor: 5.118

4.  Metabolites With Cytotoxic Activities From the Mangrove Endophytic Fungus Fusarium sp. 2ST2.

Authors:  Yan Chen; Guisheng Wang; Yilin Yuan; Ge Zou; Wencong Yang; Qi Tan; Wenyi Kang; Zhigang She
Journal:  Front Chem       Date:  2022-02-15       Impact factor: 5.221

5.  Fused multicyclic polyketides with a two-spiro-carbon skeleton from mangrove-derived endophytic fungus Epicoccum nigrum SCNU-F0002.

Authors:  Zhangyuan Yan; Jialin Li; Geting Ye; Tao Chen; Meimei Li; Yanmin Liang; Yuhua Long
Journal:  RSC Adv       Date:  2020-08-03       Impact factor: 3.361

6.  Hemiacetalmeroterpenoids A-C and Astellolide Q with Antimicrobial Activity from the Marine-Derived Fungus Penicillium sp. N-5.

Authors:  Tao Chen; Wencong Yang; Taobo Li; Yihao Yin; Yufeng Liu; Bo Wang; Zhigang She
Journal:  Mar Drugs       Date:  2022-08-13       Impact factor: 6.085

Review 7.  Unusual Secondary Metabolites from the Mangrove Ecosystems: Structures, Bioactivities, Chemical, and Bio-Syntheses.

Authors:  Meng-Jun Wu; Baofu Xu; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2022-08-20       Impact factor: 6.085

8.  Indole Diketopiperazine Alkaloids Isolated From the Marine-Derived Fungus Aspergillus chevalieri MCCC M23426.

Authors:  Dongli Lv; Jinmei Xia; Xiaoqing Guan; Qiliang Lai; Beibei Zhang; Jianhui Lin; Zongze Shao; Sulan Luo; Dongting Zhangsun; Jiang-Jiang Qin; Weiyi Wang
Journal:  Front Microbiol       Date:  2022-07-07       Impact factor: 6.064

Review 9.  Marine-Derived Indole Alkaloids and Their Biological and Pharmacological Activities.

Authors:  Joko Tri Wibowo; Peni Ahmadi; Siti Irma Rahmawati; Asep Bayu; Masteria Yunovilsa Putra; Anake Kijjoa
Journal:  Mar Drugs       Date:  2021-12-21       Impact factor: 5.118

10.  Furobenzotropolones A, B and 3-Hydroxyepicoccone B with Antioxidative Activity from Mangrove Endophytic Fungus Epicoccum nigrum MLY-3.

Authors:  Ge Zou; Qi Tan; Yan Chen; Wencong Yang; Zhenming Zang; Hongming Jiang; Shenyu Chen; Bo Wang; Zhigang She
Journal:  Mar Drugs       Date:  2021-07-14       Impact factor: 5.118

  10 in total

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