| Literature DB >> 31762277 |
Runlin Cai1, Hongming Jiang1, Zeen Xiao1, Wenhao Cao2, Tao Yan2, Zhaoming Liu1, Shao'e Lin1, Yuhua Long3, Zhigang She1,4.
Abstract
A pair of enantiomeric indole diketopiperazine alkaloid dimers [(-)- and (+)-asperginulin A (1a and 1b)] with an unprecedented 6/5/4/5/6 pentacyclic skeleton were isolated from the mangrove endophytic fungus Aspergillus sp. SK-28. The enantiomeric dimers were separated by chiral-phase HPLC. Their structures including absolute configurations were elucidated by spectroscopic analysis, X-ray diffraction, and quantum chemical calculation. (+)-Asperginulin A (1b) exhibited antifouling activity against the barnacle Balanus reticulatus.Entities:
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Year: 2019 PMID: 31762277 DOI: 10.1021/acs.orglett.9b03796
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005