Literature DB >> 3176048

Sarafotoxins S6: several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart.

C Takasaki1, N Tamiya, A Bdolah, Z Wollberg, E Kochva.   

Abstract

Three isotoxins, named sarafotoxins S6a1, S6b and S6c, with strong cardiotoxic activity were isolated from the venom of a snake, Atractaspis engaddensis. All three sarafotoxins are homologous peptides (four or less than four residue replacements) consisting of 21 amino acid residues. Their structure and activity are novel among snake venom components.

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Year:  1988        PMID: 3176048     DOI: 10.1016/0041-0101(88)90234-6

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  15 in total

1.  Endothelin regulation of neuropeptide release from nerve endings of the posterior pituitary.

Authors:  M F Ritz; E L Stuenkel; G Dayanithi; R Jones; J J Nordmann
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

Review 2.  Endothelins. Vascular actions and clinical implications.

Authors:  T Sakurai; K Goto
Journal:  Drugs       Date:  1993-11       Impact factor: 9.546

Review 3.  Privileged frameworks from snake venom.

Authors:  T A Reeks; B G Fry; P F Alewood
Journal:  Cell Mol Life Sci       Date:  2015-02-19       Impact factor: 9.261

4.  Effects of indomethacin on the regional haemodynamic responses to low doses of endothelins and sarafotoxin.

Authors:  S M Gardiner; A M Compton; T Bennett
Journal:  Br J Pharmacol       Date:  1990-05       Impact factor: 8.739

5.  An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo.

Authors:  R Lahav; G Heffner; P H Patterson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

Review 6.  Role of endothelin in hypertension.

Authors:  B K Krämer; M Ackermann; S M Kohler; G A Riegger
Journal:  Clin Investig       Date:  1994-01

7.  Themed section: endothelin.

Authors:  Anthony P Davenport; Matthias Barton
Journal:  Br J Pharmacol       Date:  2013-01       Impact factor: 8.739

8.  Tumour blood flow modification by endothelin-related peptides in the rat HSN fibrosarcoma.

Authors:  K M Bell; V E Prise; D J Chaplin; G M Tozer
Journal:  Br J Cancer Suppl       Date:  1996-07

9.  Endothelin receptor subtypes in human and guinea-pig pulmonary tissues.

Authors:  D W Hay; M A Luttmann; W C Hubbard; B J Undem
Journal:  Br J Pharmacol       Date:  1993-11       Impact factor: 8.739

10.  Sarafotoxin expression in the bronchopulmonary tract: immunohistochemical occurrence and colocalization with endothelins.

Authors:  K A Seldeslagh; J M Lauweryns
Journal:  Histochemistry       Date:  1993-10
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