Ayami Shimizu1, Ryuji Sakakibara2, Osamu Takahashi3, Fuyuki Tateno4, Yosuke Aiba5. 1. Clinical Physiology Unit, Sakura Medical Center, Toho University, 564-1 Shimoshizu, Sakura 285-8741, Japan. Electronic address: ayami.shimizu@med.toho-u.ac.jp. 2. Neurology, Internal Medicine, Sakura Medical Center, Toho University, 564-1 Shimoshizu, Sakura 285-8741, Japan. Electronic address: sakakibara@sakura.med.toho-u.ac.jp. 3. Clinical Physiology Unit, Sakura Medical Center, Toho University, 564-1 Shimoshizu, Sakura 285-8741, Japan. Electronic address: runner@sakura.med.toho-u.ac.jp. 4. Neurology, Internal Medicine, Sakura Medical Center, Toho University, 564-1 Shimoshizu, Sakura 285-8741, Japan. Electronic address: f-tateno@sakura.med.toho-u.ac.jp. 5. Neurology, Internal Medicine, Sakura Medical Center, Toho University, 564-1 Shimoshizu, Sakura 285-8741, Japan. Electronic address: yousuke.aiba@med.toho-u.ac.jp.
Abstract
OBJECTIVE: Several studies have shown relationship between the lower urinary tract dysfunction (LUTD) and atherosclerosis. However, no study is available to see which LUTD relates more to atherosclerosis, among detrusor overactivity and post-void residual. In order to answer this question, we present data of urodynamic and atherosclerosis tests. METHODS: We performed standard urodynamics and two atherosclerosis tests, i.e., a cardio-ankle vascular stiffness index (CAVI) test and a duplex carotid ultrasonography. PATIENTS: We have 183 patients; 109 men (mean age 66.3 years), 74 women (mean age 66.4 years); all age > 60 years. RESULTS: Detrusor overactivity is related with high CAVI value (p < 0.05) but not with carotid intima-media thickness. Post-void residuals did not show such relation. CONCLUSION: Urodynamic LUTD, particularly detrusor overactivity that may indicate central etiology is positively related with systemic atherosclerosis as measured by CAVI. Post-void residuals that may indicate peripheral etiology did not show such relation.
OBJECTIVE: Several studies have shown relationship between the lower urinary tract dysfunction (LUTD) and atherosclerosis. However, no study is available to see which LUTD relates more to atherosclerosis, among detrusor overactivity and post-void residual. In order to answer this question, we present data of urodynamic and atherosclerosis tests. METHODS: We performed standard urodynamics and two atherosclerosis tests, i.e., a cardio-ankle vascular stiffness index (CAVI) test and a duplex carotid ultrasonography. PATIENTS: We have 183 patients; 109 men (mean age 66.3 years), 74 women (mean age 66.4 years); all age > 60 years. RESULTS: Detrusor overactivity is related with high CAVI value (p < 0.05) but not with carotid intima-media thickness. Post-void residuals did not show such relation. CONCLUSION: Urodynamic LUTD, particularly detrusor overactivity that may indicate central etiology is positively related with systemic atherosclerosis as measured by CAVI. Post-void residuals that may indicate peripheral etiology did not show such relation.