Behnaz Moradi1, Maryam Rahmani2, Kolsoom Kia3, Mohammad Ali Kazemi4, Ahmad-Reza Tahmasebpour5. 1. Department of Radiology, Women' Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2. Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. 3. Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: hkia2001@gmail.com. 4. Department of Radiology, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran. 5. Iranian Fetal Medicine Foundation, Hope Generation Foundation, Tehran, Iran.
Abstract
OBJECTIVE: Cavum veli interpositi (CVI) is a potential space below the splenium of corpus callosum and sometimes presents as a cyst. MATERIALS AND METHODS: In this prospective cross-sectional study, 360 fetuses with normal second trimester scan and 152 s trimester fetuses with structural abnormalities were included. RESULTS: The CVI cysts were more common in fetuses with brain anomaly compared to normal fetuses and fetuses with extra-central nervous system (CNS) anomalies (23% vs 18.3% and 18% respectively; p value < 0.01). The mean size of cysts in normal fetuses, fetuses with extra-CNS anomalies and fetuses with brain abnormalities was 4.6 mm, 5.8 mm and 9.2 mm respectively. There was a significant difference between cysts size in normal fetuses and fetuses with brain anomalies (p value < 0.01) and the cut-point was 7.1 mm. CONCLUSION: The prevalence of CVI cysts is more in fetuses with brain anomaly. Fetuses with a cyst size >7.1 mm need a more detailed brain examination.
OBJECTIVE: Cavum veli interpositi (CVI) is a potential space below the splenium of corpus callosum and sometimes presents as a cyst. MATERIALS AND METHODS: In this prospective cross-sectional study, 360 fetuses with normal second trimester scan and 152 s trimester fetuses with structural abnormalities were included. RESULTS: The CVI cysts were more common in fetuses with brain anomaly compared to normal fetuses and fetuses with extra-central nervous system (CNS) anomalies (23% vs 18.3% and 18% respectively; p value < 0.01). The mean size of cysts in normal fetuses, fetuses with extra-CNS anomalies and fetuses with brain abnormalities was 4.6 mm, 5.8 mm and 9.2 mm respectively. There was a significant difference between cysts size in normal fetuses and fetuses with brain anomalies (p value < 0.01) and the cut-point was 7.1 mm. CONCLUSION: The prevalence of CVI cysts is more in fetuses with brain anomaly. Fetuses with a cyst size >7.1 mm need a more detailed brain examination.
Authors: Giulio Giordano; Giovanni L Tiscia; Giovanni Favuzzi; Elena Chinni; Mariano Intrieri; Mario Mastroianno; Letizia Di Meglio; Maurizio Margaglione; Elvira Grandone Journal: BMC Pregnancy Childbirth Date: 2020-12-11 Impact factor: 3.007