| Literature DB >> 3175952 |
Abstract
Identification of sex is often necessary to evaluate genetic or teratogenetic effects on embryonic development. A simple molecular technique to identify the sex of mouse embryos was studied using a Y chromosomal repetitive sequence (designated 145SC5). Since this technique does not require purification of DNA, it is particularly suitable for processing many embryos. Furthermore, 145SC5 detects 1% contamination of male DNA in a male-female DNA mixture. These results suggest that 145SC5 is a powerful molecular tool in a variety of studies on mouse development.Entities:
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Year: 1988 PMID： 3175952 DOI： 10.1002/tera.1420380211
Source DB: PubMed Journal: Teratology ISSN： 0040-3709