Literature DB >> 31758535

Control of Regulatory T Cells by Co-signal Molecules.

James Badger Wing1, Christopher Tay1, Shimon Sakaguchi2,3.   

Abstract

Foxp3-expressing regulatory T cells (Tregs) perform a vital function in the maintenance of immune homeostasis. A large part of Treg suppressive function is derived from their ability to control and restrict the availability of co-signal molecules to other T cells. However, Tregs themselves also depend on many of the same co-signals for their own homeostasis, making this a complex system of feedback. In this chapter, we discuss the critical role of co-signaling in Treg cell biology.

Entities:  

Keywords:  CD27; CD28; CD30; CTLA-4; DR3; GITR; ICOS; OX40; PD-1; TIGIT; TNFR2; Tim-3; Tregs

Mesh：

Substances：

Year:  2019        PMID： 31758535     DOI： 10.1007/978-981-32-9717-3_7

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  13 in total

1.  Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice.

Authors:  Ashley N Suah; Dong-Kha V Tran; Stella Hw Khiew; Michael S Andrade; Jared M Pollard; Dharmendra Jain; James S Young; Dengping Yin; Geetha Chalasani; Maria-Luisa Alegre; Anita S Chong
Journal:  J Clin Invest       Date:  2021-01-04       Impact factor: 14.808

2.  Optimal target saturation of ligand-blocking anti-GITR antibody IBI37G5 dictates FcγR-independent GITR agonism and antitumor activity.

Authors:  Huisi Liu; Weiwei Wu; Gangyu Sun; Tiongsun Chia; Lei Cao; Xiaodan Liu; Jian Guan; Fenggen Fu; Ying Yao; Zhihai Wu; Shuaixiang Zhou; Jie Wang; Jia Lu; Zhihui Kuang; Min Wu; Luan He; Zhiyuan Shao; Dongdong Wu; Bingliang Chen; Wenqing Xu; Zhizhi Wang; Kaijie He
Journal:  Cell Rep Med       Date:  2022-06-21

3.  miR-33 Silencing Reprograms the Immune Cell Landscape in Atherosclerotic Plaques.

Authors:  Milessa Silva Afonso; Monika Sharma; Martin Schlegel; Coen van Solingen; Graeme J Koelwyn; Lianne C Shanley; Lauren Beckett; Daniel Peled; Karishma Rahman; Chiara Giannarelli; Huilin Li; Emily J Brown; Alireza Khodadadi-Jamayran; Edward A Fisher; Kathryn J Moore
Journal:  Circ Res       Date:  2021-02-17       Impact factor: 17.367

4.  T cell transgressions: Tales of T cell form and function in diverse disease states.

Authors:  Kevin M Harris; Madison A Clements; Andrew J Kwilasz; Linda R Watkins
Journal:  Int Rev Immunol       Date:  2021-06-21       Impact factor: 5.078

5.  High proportion of terminally differentiated regulatory T cells after allogeneic hematopoietic stem cell transplantation.

Authors:  Caroline Ritacco; Grégory Ehx; Céline Grégoire; Coline Daulne; Evelyne Willems; Sophie Servais; Yves Beguin; Frédéric Baron
Journal:  Bone Marrow Transplant       Date:  2021-03-04       Impact factor: 5.174

6.  The effects of TNF-α/TNFR2 in regulatory T cells on the microenvironment and progression of gastric cancer.

Authors:  Yang Qu; Xianhao Wang; Shuai Bai; Liling Niu; Gang Zhao; Yuan Yao; Bin Li; Hui Li
Journal:  Int J Cancer       Date:  2021-11-16       Impact factor: 7.316

Review 7.  The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens.

Authors:  Jose-Ignacio Rodriguez-Barbosa; Pascal Schneider; Luis Graca; Leo Bühler; Jose-Antonio Perez-Simon; Maria-Luisa Del Rio
Journal:  Int J Mol Sci       Date:  2020-05-09       Impact factor: 5.923

Review 8.  A 21st Century Evil: Immunopathology and New Therapies of COVID-19.

Authors:  Taylon Felipe Silva; Fernanda Tomiotto-Pellissier; Raquel Arruda Sanfelice; Manoela Daiele Gonçalves; Bruna Taciane da Silva Bortoleti; Mariana Barbosa Detoni; Ana Carolina Jacob Rodrigues; Amanda Cristina Machado Carloto; Virgínia Márcia Concato; Elaine da Silva Siqueira; Idessania Nazareth Costa; Wander Rogério Pavanelli; Ivete Conchon-Costa; Milena Menegazzo Miranda-Sapla
Journal:  Front Immunol       Date:  2020-10-27       Impact factor: 7.561

Review 9.  Nucleic Acid-Based Approaches for Tumor Therapy.

Authors:  Simone Hager; Frederic Julien Fittler; Ernst Wagner; Matthias Bros
Journal:  Cells       Date:  2020-09-09       Impact factor: 6.600

10.  TIGIT modulates sepsis-induced immune dysregulation in mice with preexisting malignancy.

Authors:  Wenxiao Zhang; Jerome C Anyalebechi; Kimberly M Ramonell; Ching-Wen Chen; Jianfeng Xie; Zhe Liang; Deena B Chihade; Shunsuke Otani; Craig M Coopersmith; Mandy L Ford
Journal:  JCI Insight       Date:  2021-06-08
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