Aitor Fernández-García1, Ying Zhou1, Mercedes García-Alonso2, Henry D Andrango2, Francisco Poyales1, Nuria Garzón3,4. 1. IOA Madrid, C/Galileo 104, 28003, Madrid, Spain. 2. Optometry and Vision Department, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain. 3. IOA Madrid, C/Galileo 104, 28003, Madrid, Spain. ngarzon@ioamadrid.com. 4. Optometry and Vision Department, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain. ngarzon@ioamadrid.com.
Abstract
PURPOSE: To evaluate medium-term clinical outcomes with microstent XEN® 45 Gel Stent (Allergan Dublin, Ireland) for treatment of primary open-angle glaucoma (POAG). MATERIAL AND METHODS: This is a retrospective, descriptive and observational study involving 93 eyes from 63 patients who had undergone POAG surgery with a XEN® 45 Gel Stent implantation and had been followed up and controlled between 12 and 36 months. RESULTS: IOP dropped from 18.23 ± 5.00 mmHg pre-op to 14.16 ± 2.14, 14.47 ± 2.16 and 14.63 ± 1.91 at 1, 2 and 3 years after surgery (p = 0.000, 0.000 and 0.001) consecutively. Mean number of medications dropped from 1.87 ± 0.94 preoperatively to 0.31 ± 0.69, 0.34 ± 0.63 and 1.00 ± 0.88 (p = 0.000, 0.000 and 0.017) at 12, 24 and 36 months. Mean visual field deviation values never turned out to be significant for any of the follow-up visit data. A total of 94.6% of the surgical procedures turned out to be complication-free. In one surgery, the procedure failed and 18 months later other device was implanted. CONCLUSION: POAG surgical procedures with XEN® 45 Gel Stent implants are a safe and effective treatment approach.
PURPOSE: To evaluate medium-term clinical outcomes with microstent XEN® 45 Gel Stent (Allergan Dublin, Ireland) for treatment of primary open-angle glaucoma (POAG). MATERIAL AND METHODS: This is a retrospective, descriptive and observational study involving 93 eyes from 63 patients who had undergone POAG surgery with a XEN® 45 Gel Stent implantation and had been followed up and controlled between 12 and 36 months. RESULTS: IOP dropped from 18.23 ± 5.00 mmHg pre-op to 14.16 ± 2.14, 14.47 ± 2.16 and 14.63 ± 1.91 at 1, 2 and 3 years after surgery (p = 0.000, 0.000 and 0.001) consecutively. Mean number of medications dropped from 1.87 ± 0.94 preoperatively to 0.31 ± 0.69, 0.34 ± 0.63 and 1.00 ± 0.88 (p = 0.000, 0.000 and 0.017) at 12, 24 and 36 months. Mean visual field deviation values never turned out to be significant for any of the follow-up visit data. A total of 94.6% of the surgical procedures turned out to be complication-free. In one surgery, the procedure failed and 18 months later other device was implanted. CONCLUSION: POAG surgical procedures with XEN® 45 Gel Stent implants are a safe and effective treatment approach.
Authors: Arsham Sheybani; Markus Lenzhofer; Melchior Hohensinn; Herbert Reitsamer; Iqbal Ike K Ahmed Journal: J Cataract Refract Surg Date: 2015-10-23 Impact factor: 3.351
Authors: Huub J Poelman; Jan Pals; Parinaz Rostamzad; Wichor M Bramer; Roger C W Wolfs; Wishal D Ramdas Journal: J Clin Med Date: 2021-03-07 Impact factor: 4.241
Authors: Inês C F Pereira; Rosanne van de Wijdeven; Hans M Wyss; Henny J M Beckers; Jaap M J den Toonder Journal: Eye (Lond) Date: 2021-06-14 Impact factor: 3.775