Literature DB >> 31756330

Dawn of a New Era of Targeted Antioxidant Therapies.

Brent R Stockwell1.   

Abstract

In this issue of Cell Chemical Biology, Shah et al. (2019) report an in vitro, high-throughput assay that predicts the ability of compounds to suppress peroxidation of phospholipids. This approach provides a way to design and optimize targeted antioxidants that suppress specific oxidative event in cells, potentially overcoming previous failures with generic antioxidants.
Copyright © 2019 Elsevier Ltd. All rights reserved.

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Year:  2019        PMID: 31756330      PMCID: PMC7245533          DOI: 10.1016/j.chembiol.2019.11.003

Source DB:  PubMed          Journal:  Cell Chem Biol        ISSN: 2451-9448            Impact factor:   8.116


  9 in total

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Journal:  Nature       Date:  1954-10-09       Impact factor: 49.962

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Authors:  H HARTLEY
Journal:  Nature       Date:  1951-08-11       Impact factor: 49.962

Review 3.  Methods for determining the efficacy of radical-trapping antioxidants.

Authors:  Bo Li; Derek A Pratt
Journal:  Free Radic Biol Med       Date:  2015-02-04       Impact factor: 7.376

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Authors:  H A MATTILL
Journal:  Annu Rev Biochem       Date:  1947       Impact factor: 23.643

Review 5.  Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis.

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Journal:  Br J Exp Pathol       Date:  1989-12

Review 6.  Oxidative Stress.

Authors:  Helmut Sies; Carsten Berndt; Dean P Jones
Journal:  Annu Rev Biochem       Date:  2017-04-24       Impact factor: 23.643

7.  Beyond DPPH: Use of Fluorescence-Enabled Inhibited Autoxidation to Predict Oxidative Cell Death Rescue.

Authors:  Ron Shah; Luke A Farmer; Omkar Zilka; Antonius T M Van Kessel; Derek A Pratt
Journal:  Cell Chem Biol       Date:  2019-09-26       Impact factor: 8.116

Review 8.  The development of the concept of ferroptosis.

Authors:  Tal Hirschhorn; Brent R Stockwell
Journal:  Free Radic Biol Med       Date:  2018-09-28       Impact factor: 7.376

9.  Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis.

Authors:  Michael M Gaschler; Fanghao Hu; Huizhong Feng; Andreas Linkermann; Wei Min; Brent R Stockwell
Journal:  ACS Chem Biol       Date:  2018-03-13       Impact factor: 5.100

  9 in total

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