Literature DB >> 31755469

Commentary: Vitrectomy as a treatment modality in vitreous seeding secondary to ciliary body melanocytoma.

Pukhraj Rishi1.   

Abstract

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Year:  2019        PMID: 31755469      PMCID: PMC6896569          DOI: 10.4103/ijo.IJO_1119_19

Source DB:  PubMed          Journal:  Indian J Ophthalmol        ISSN: 0301-4738            Impact factor:   1.848


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The variation in the presentation of anterior uveal tumors throws up several possibilities related to their management. Diagnostic work-up with slit-lamp examination, gonioscopy, transillumination test, ultrasound biomicroscopy (UBM), fluorescein angiography, and magnetic resonance imaging (MRI) help to reach a provisional diagnosis. One needs to establish the cystic/solid and melanocytic/nonmelanocytic nature of the tumor, and a decision about FNAC[1]/incision/excision biopsy[2345] is arrived at depending on the tumor size, location, and surgeon's familiarity of the biopsy technique. Often, the benign/malignant nature of the tumor can be established with this approach using histopathological and immunohistochemistry testing and a treatment plan is put in place. While benign, nonprogressive tumors can be observed, intervention is required for malignant or progressively enlarging tumors. In literature with adult subjects, surgical excision is successful for globe salvage in 71--81% with final visual acuity of ≥20/40 achieved in 50--53%, but has its own share of complications. [234] Complete surgical excision of intraocular tumor with established pathological evaluation leads to favorable long-term outcomes. Management options for tumors with an established diagnosis of CB melanocytoma include observation, plaque radiation,[6] surgical excision, or enucleation. In the current study,[7] the authors have done well to surgically remove the dense pigmented vitreous floaters and achieved gratifying visual outcome. However, this report throws up other pertinent questions that the literature is deficient about. How does one predict the risk of recurrences of necrosis and pigment release, besides the rare possibility of malignant transformation?[8]
  8 in total

1.  Iridociliochoroidal melanoma arising from melanocytoma in a black teenager.

Authors:  Helen K Li; Carol L Shields; Jerry A Shields; Ralph C Eagle; John O Mason
Journal:  J AAPOS       Date:  2010-04       Impact factor: 1.220

2.  The role of eyewall resection in uveal melanoma management.

Authors:  Bertil Damato
Journal:  Int Ophthalmol Clin       Date:  2006

3.  Melanocytoma of the ciliary body diagnosed by fine-needle aspiration biopsy.

Authors:  S M El-Harazi; J Kellaway; R L Font
Journal:  Diagn Cytopathol       Date:  2000-06       Impact factor: 1.582

4.  Uveal tumour resection.

Authors:  D H Char; T Miller; J B Crawford
Journal:  Br J Ophthalmol       Date:  2001-10       Impact factor: 4.638

5.  Partial lamellar sclerouvectomy for ciliary body and choroidal tumors.

Authors:  J A Shields; C L Shields; P Shah; V Sivalingam
Journal:  Ophthalmology       Date:  1991-06       Impact factor: 12.079

6.  Brachytherapy, a viable option of globe salvage in treatment of large ciliary body melanocytoma.

Authors:  Mahesh P Shanmugam; Manish Saxena; Rajesh Ramanjulu; Pradeep Tekwani
Journal:  Indian J Ophthalmol       Date:  2014-09       Impact factor: 1.848

Review 7.  Biopsy techniques for intraocular tumors.

Authors:  Pukhraj Rishi; Abhinav Dhami; Jyotirmay Biswas
Journal:  Indian J Ophthalmol       Date:  2016-06       Impact factor: 1.848

8.  Vitrectomy as a treatment modality in vitreous seeding secondary to ciliary body melanocytoma.

Authors:  P Mahesh Shanmugam; Ishfaq A Sofi; Pradeep Sagar; Vinaya K Konana; Rajesh Ramanjulu
Journal:  Indian J Ophthalmol       Date:  2019-12       Impact factor: 1.848

  8 in total

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