Abhishek S Chitnis1, Mollie Vanderkarr2, Charisse Sparks3, Jonathan McGlohorn4, Chantal E Holy1. 1. Medical Devices Epidemiology, Real World Data Sciences, Johnson & Johnson, New Brunswick, NJ 08901, USA. 2. Health Economics Market Access, DePuy Synthes Orthopaedics, West Chester, PA 19380, USA. 3. Medical Affairs, DePuy Synthes Orthopaedics, West Chester, PA 19380, USA. 4. Clinical Research, DePuy Synthes Switzerland, Solothurn, 4528, Switzerland.
Abstract
Aim: To evaluate the rates of infection and nonunion and determine the impact of infections on healthcare resource use and costs following open and closed fractures of the tibial shaft requiring open reduction internal fixation. Methods: Healthcare use and costs were compared between patients with and without infections following pen reduction internal fixation using MarketScan® databases. Results: For commercial patients, the rates of infection and nonunion ranged from 1.82 to 7.44% and 0.48 to 8.75%, respectively, over the 2-year period. Patients with infection had significantly higher rates of hospital readmissions, emergency room visits and healthcare costs compared with patients without infection. Conclusion: This real-world study showed an increasing rate of infection up to 2 years and infection significantly increased healthcare resource use and costs.
Aim: To evaluate the rates of infection and nonunion and determine the impact of infections on healthcare resource use and costs following open and closed fractures of the tibial shaft requiring open reduction internal fixation. Methods: Healthcare use and costs were compared between patients with and without infections following pen reduction internal fixation using MarketScan® databases. Results: For commercial patients, the rates of infection and nonunion ranged from 1.82 to 7.44% and 0.48 to 8.75%, respectively, over the 2-year period. Patients with infection had significantly higher rates of hospital readmissions, emergency room visits and healthcare costs compared with patients without infection. Conclusion: This real-world study showed an increasing rate of infection up to 2 years and infection significantly increased healthcare resource use and costs.
Authors: Heather J Roberts; Claire A Donnelley; Billy T Haonga; Erik Kramer; Edmund N Eliezer; Saam Morshed; David Shearer Journal: OTA Int Date: 2021-08-09
Authors: Madeleine C Stevenson; Julia C Slater; H Claude Sagi; Federico Palacio Bedoya; Margaret V Powers-Fletcher Journal: J Clin Microbiol Date: 2021-06-16 Impact factor: 11.677