| Literature DB >> 31754599 |
Ruby Dwivedi1, Rahul Pandey2, Sumit Kumar2, Divya Mehrotra2.
Abstract
Polyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffolds in bone tissue engineering. This review describes in brief the production and extraction sources, physico-chemical characteristic, mechanical properties, degradation rate and applications of various PHAs and its copolymers with special emphasis to its role as scaffolds in bone tissue engineering.Entities:
Keywords: Bone tissue engineering; Polyhydroxyalkanoates; Polyhydroxybutyrate; Scaffolds
Year: 2019 PMID: 31754599 PMCID: PMC6854076 DOI: 10.1016/j.jobcr.2019.10.004
Source DB: PubMed Journal: J Oral Biol Craniofac Res ISSN: 2212-4268