Literature DB >> 31754599

Poly hydroxyalkanoates (PHA): Role in bone scaffolds.

Ruby Dwivedi1, Rahul Pandey2, Sumit Kumar2, Divya Mehrotra2.   

Abstract

Polyhydroxyalkanoates (PHA) are prokaryotic macromolecules accumulated within the cytoplasm as granules. Due to their suitable mechanical properties, biocompatibility, degradation time, ability to be blended, surface modified, and form copolymers, it is widely used in medical devices and as scaffolds in bone tissue engineering. This review describes in brief the production and extraction sources, physico-chemical characteristic, mechanical properties, degradation rate and applications of various PHAs and its copolymers with special emphasis to its role as scaffolds in bone tissue engineering.
© 2019 Published by Elsevier B.V. on behalf of Craniofacial Research Foundation.

Entities:  

Keywords:  Bone tissue engineering; Polyhydroxyalkanoates; Polyhydroxybutyrate; Scaffolds

Year:  2019        PMID: 31754599      PMCID: PMC6854076          DOI: 10.1016/j.jobcr.2019.10.004

Source DB:  PubMed          Journal:  J Oral Biol Craniofac Res        ISSN: 2212-4268


  20 in total

1.  The application of polyhydroxyalkanoates as tissue engineering materials.

Authors:  Guo-Qiang Chen; Qiong Wu
Journal:  Biomaterials       Date:  2005-11       Impact factor: 12.479

2.  Crystallization and its effect on the mechanical properties of a medium chain length polyhydroxyalkanoate.

Authors:  A Larrañaga; J Fernández; A Vega; A Etxeberria; C Ronchel; J L Adrio; J R Sarasua
Journal:  J Mech Behav Biomed Mater       Date:  2014-07-29

3.  A Micro-Ark for Cells: Highly Open Porous Polyhydroxyalkanoate Microspheres as Injectable Scaffolds for Tissue Regeneration.

Authors:  Dai-Xu Wei; Jin-Wei Dao; Guo-Qiang Chen
Journal:  Adv Mater       Date:  2018-06-19       Impact factor: 30.849

4.  Chondrogenic differentiation of human bone marrow mesenchymal stem cells on polyhydroxyalkanoate (PHA) scaffolds coated with PHA granule binding protein PhaP fused with RGD peptide.

Authors:  Mingliang You; Gongfeng Peng; Jian Li; Ping Ma; Zhihui Wang; Weiliang Shu; Siwu Peng; Guo-Qiang Chen
Journal:  Biomaterials       Date:  2010-12-28       Impact factor: 12.479

5.  Bacterial polyhydroxyalkanoates.

Authors:  S Y Lee
Journal:  Biotechnol Bioeng       Date:  1996-01-05       Impact factor: 4.530

6.  Tissue response to the implantation of biodegradable polyhydroxyalkanoate sutures.

Authors:  E I Shishatskaya; T G Volova; A P Puzyr; O A Mogilnaya; S N Efremov
Journal:  J Mater Sci Mater Med       Date:  2004-06       Impact factor: 3.896

Review 7.  Polyhydroxyalkanoates: Much More than Biodegradable Plastics.

Authors:  Nancy I López; M Julia Pettinari; Pablo I Nikel; Beatriz S Méndez
Journal:  Adv Appl Microbiol       Date:  2015-07-14       Impact factor: 5.086

8.  Electrospun polyhydroxybutyrate and poly(L-lactide-co-ε-caprolactone) composites as nanofibrous scaffolds.

Authors:  Donraporn Daranarong; Rodman T H Chan; Nico S Wanandy; Robert Molloy; Winita Punyodom; L John R Foster
Journal:  Biomed Res Int       Date:  2014-05-08       Impact factor: 3.411

9.  Additive Manufacturing of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)/poly(ε-caprolactone) Blend Scaffolds for Tissue Engineering.

Authors:  Dario Puppi; Andrea Morelli; Federica Chiellini
Journal:  Bioengineering (Basel)       Date:  2017-05-24

Review 10.  Biodegradable and Biocompatible Polyhydroxy-alkanoates (PHA): Auspicious Microbial Macromolecules for Pharmaceutical and Therapeutic Applications.

Authors:  Martin Koller
Journal:  Molecules       Date:  2018-02-08       Impact factor: 4.411

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  15 in total

1.  Study of the Production of Poly(Hydroxybutyrate-co-Hydroxyhexanoate) and Poly(Hydroxybutyrate-co-Hydroxyvalerate-co-Hydroxyhexanoate) in Rhodospirillum rubrum.

Authors:  Paloma Cabecas Segura; Rob Onderwater; Adam Deutschbauer; Laurent Dewasme; Ruddy Wattiez; Baptiste Leroy
Journal:  Appl Environ Microbiol       Date:  2022-01-26       Impact factor: 5.005

2.  Production and characterization of polyhydroxyalkanoates from industrial waste using soil bacterial isolates.

Authors:  Shreya Shah; Anil Kumar
Journal:  Braz J Microbiol       Date:  2021-02-15       Impact factor: 2.476

3.  Demonstrating the Potential of Using Bio-Based Sustainable Polyester Blends for Bone Tissue Engineering Applications.

Authors:  David H Ramos-Rodriguez; Samand Pashneh-Tala; Amanpreet Kaur Bains; Robert D Moorehead; Nikolaos Kassos; Adrian L Kelly; Thomas E Paterson; C Amnael Orozco-Diaz; Andrew A Gill; Ilida Ortega Asencio
Journal:  Bioengineering (Basel)       Date:  2022-04-06

Review 4.  Plastic accumulation during COVID-19: call for another pandemic; bioplastic a step towards this challenge?

Authors:  Mahak Mittal; Divya Mittal; Neeraj K Aggarwal
Journal:  Environ Sci Pollut Res Int       Date:  2022-01-13       Impact factor: 5.190

Review 5.  Therapeutic Treatments for Osteoporosis-Which Combination of Pills Is the Best among the Bad?

Authors:  Christian Horst Tonk; Sarah Hani Shoushrah; Patrick Babczyk; Basma El Khaldi-Hansen; Margit Schulze; Monika Herten; Edda Tobiasch
Journal:  Int J Mol Sci       Date:  2022-01-26       Impact factor: 5.923

6.  In Vitro Characterization of Poly(Lactic Acid)/ Poly(Hydroxybutyrate)/ Thermoplastic Starch Blends for Tissue Engineering Application.

Authors:  Martina Culenova; Ivana Birova; Pavol Alexy; Paulina Galfyova; Andreas Nicodemou; Barbora Moncmanova; Roderik Plavec; Katarina Tomanova; Premysl Mencik; Stanislav Ziaran; Lubos Danisovic
Journal:  Cell Transplant       Date:  2021 Jan-Dec       Impact factor: 4.064

7.  Laser Processing of Polymer Films Fabricated from PHAs Differing in Their Monomer Composition.

Authors:  Tatiana G Volova; Alexey I Golubev; Ivan V Nemtsev; Anna V Lukyanenko; Alexey E Dudaev; Ekaterina I Shishatskaya
Journal:  Polymers (Basel)       Date:  2021-05-12       Impact factor: 4.329

8.  Elucidating the Surface Functionality of Biomimetic RGD Peptides Immobilized on Nano-P(3HB-co-4HB) for H9c2 Myoblast Cell Proliferation.

Authors:  Sevakumaran Vigneswari; Jun Meng Chai; Khadijah Hilmun Kamarudin; Al-Ashraf Abdullah Amirul; Maria Letizia Focarete; Seeram Ramakrishna
Journal:  Front Bioeng Biotechnol       Date:  2020-10-27

9.  Photoautotrophic and Mixotrophic Cultivation of Polyhydroxyalkanoate-Accumulating Microalgae Consortia Selected under Nitrogen and Phosphate Limitation.

Authors:  Parichat Phalanisong; Pensri Plangklang; Alissara Reungsang
Journal:  Molecules       Date:  2021-12-15       Impact factor: 4.411

Review 10.  Innovative Molecular and Cellular Therapeutics in Cleft Palate Tissue Engineering.

Authors:  Jeremie D Oliver; Shihai Jia; Leslie R Halpern; Emily M Graham; Emma C Turner; John S Colombo; David W Grainger; Rena N D'Souza
Journal:  Tissue Eng Part B Rev       Date:  2020-09-28       Impact factor: 7.376

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