| Literature DB >> 31753132 |
Yaakov Stern1, Daniel Barulli2.
Abstract
Cognitive reserve is a latent construct theorized to account for the discrepancy between observed brain deterioration and ultimate clinical outcomes. This review outlines the theoretical development of the reserve concept and presents major trends within epidemiological and neuroimaging research literatures in support of such a construct. Particular focus is placed on the implications for cognitive aging and dementia.Entities:
Keywords: Aging; Compensation; Dementia; Epidemiology; Neuroimaging; fMRI
Mesh:
Year: 2019 PMID: 31753132 DOI: 10.1016/B978-0-12-804766-8.00011-X
Source DB: PubMed Journal: Handb Clin Neurol ISSN: 0072-9752