Literature DB >> 31748769

Nickel-catalyzed electrochemical reductive decarboxylative coupling of N-hydroxyphthalimide esters with quinoxalinones.

Fei Lian1, Kun Xu2, Wei Meng1, Haonan Zhang1, Zhoumei Tan1, Chengchu Zeng1.   

Abstract

Herein the first example of electrochemically enabled, NiCl2-catalyzed reductive decarboxylative coupling of N-hydroxyphthalimide (NHP) esters with quinoxalinones is reported. A range of primary, secondary, tertiary aliphatic carboxylic acids and amino acid-derived esters were tolerated well. This decarboxylative coupling allows access to structurally diverse 3-alkylated quinoxalinones in up to 91% yields.

Entities:  

Year:  2019        PMID： 31748769     DOI： 10.1039/c9cc07840a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  General electrochemical Minisci alkylation of N-heteroarenes with alkyl halides.

Authors:  Roberto Del Río-Rodríguez; Lorena Fragoso-Jarillo; Alberto F Garrido-Castro; M Carmen Maestro; Jose A Fernández-Salas; José Alemán
Journal:  Chem Sci       Date:  2022-05-06       Impact factor: 9.969

2.  Electrochemical Nozaki-Hiyama-Kishi Coupling: Scope, Applications, and Mechanism.

Authors:  Yang Gao; David E Hill; Wei Hao; Brendon J McNicholas; Julien C Vantourout; Ryan G Hadt; Sarah E Reisman; Donna G Blackmond; Phil S Baran
Journal:  J Am Chem Soc       Date:  2021-06-15       Impact factor: 16.383

3.  Photoinitiated decarboxylative C3-difluoroarylmethylation of quinoxalin-2(1H)-ones with potassium 2,2-difluoro-2-arylacetates in water.

Authors:  Yanhui Gao; Lulu Zhao; Tianyi Xiang; Pinhua Li; Lei Wang
Journal:  RSC Adv       Date:  2020-03-12       Impact factor: 4.036
  3 in total

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