Could there be a relation between Steven-Johnson syndrome and ST-segment elevation myocardial infarction?

Steven-Johnson syndrome (SJS) is a rare but serious mucocutaneous reaction to medications. We present a rare case of SJS developing after antibiotic administration for a lower respiratory tract infection and whose inpatient course was complicated with an acute ST-segment elevation myocardial infarction (MI). The laboratory findings revealed thrombocytosis which was possibly reactive and explained the underlying pathophysiology of the thrombus formation seen in the coronary artery. Stenting and aspiration of thrombus was performed. This case illustrates a possibly rare association between SJS and MI. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.