Literature DB >> 31747557

Prevention and treatment of chronic heart failure through traditional Chinese medicine: Role of the gut microbiota.

Qiujin Jia1, Lirong Wang1, Xiaonan Zhang1, Yuejia Ding1, Hao Li1, Yingxi Yang1, Ao Zhang2, Yanyang Li3, Shichao Lv4, Junping Zhang5.   

Abstract

In recent years, although the concept and means of modern treatment of chronic heart failure(CHF) are continually improving, the readmission rate and mortality rate are still high. At present, there is evidence that there is a link between gut microbiota and heart failure, so the intervention of gut microbiota and its metabolites is expected to become a potential new therapeutic target in heart failure. Traditional Chinese medicine(TCM) has apparent advantages in stabilizing the disease, improving heart function, and improving the quality of life. It can exert its effect by operating in the gut microbiota and is an ideal intestinal micro-ecological regulator. Therefore, this article will mainly discuss the advantages of traditional Chinese medicine in treating CHF, the relationship between traditional Chinese medicine and gut microbiota, the relationship between CHF and gut microbiota, and the ways of regulating gut microbiota by traditional Chinese medicine to prevent and treat CHF. It will specify the target and mechanism of traditional Chinese medicine treating heart failure by acting gut microbiota and provide ideas for the treatment of heart failure.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Chronic heart failure; Gut Microbiota; Traditional Chinese medicine; Treatment

Mesh:

Substances:

Year:  2019        PMID: 31747557     DOI: 10.1016/j.phrs.2019.104552

Source DB:  PubMed          Journal:  Pharmacol Res        ISSN: 1043-6618            Impact factor:   7.658


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