Literature DB >> 31746675

Surgical treatment of therapy-resistant reflux after Roux-en-Y gastric bypass. A case series of the modified Nissen fundoplication.

Jan Colpaert1, Julie Horevoets1, Leander Maes1, Gilles Uijtterhaegen1, Bruno Dillemans1.   

Abstract

Introduction: Patients with intractable reflux after RYGB have limited treatment options. Here a modified Nissen fundoplication (MNF) as described by N. Kawahara might be the answer.
Methods: In this retrospective case study we identified six patients with therapy-resistant GERD after RYGB. All six were treated with a MNF, using the remnant stomach to construct the fundoplication. Short term follow-up 1 month and 6-12 months postoperatively was conducted to inquire about GERD symptoms.
Results: Six patients underwent a MNF. Three out of six patients had had a gastric band in their medical history. Upper GI barium swallow test revealed herniation of the gastric pouch in 4/6 patients. After surgery all patients were symptom free and 4/6 completely stopped PPI treatment.Discussion: Mechanisms of new onset or deteriorating GERD after RYGB are herniation of gastric pouch and destruction of the lower esophageal sphincter after banding. Both problems are tackled when constructing a MNF.
Conclusion: Complete symptom relief was seen 1 month after MNF. The procedure seems safe, feasible and effective. The study is limited by small sample size and short follow-up yet shows clear improvement of symptoms. Larger trials are needed to establish validity of the MNF.

Entities:  

Keywords:  GERD; Gastro-esophageal reflux; Nissen fundoplication; Roux-en-Y gastric bypass; modified Nissen fundoplication; obesity

Mesh:

Year:  2019        PMID: 31746675     DOI: 10.1080/00015458.2019.1696028

Source DB:  PubMed          Journal:  Acta Chir Belg        ISSN: 0001-5458            Impact factor:   1.090


  2 in total

Review 1.  The Effect of Bariatric Surgery and Endoscopic Procedures on Gastroesophageal Reflux Disease.

Authors:  Ofer Z Fass; Hiroshi Mashimo
Journal:  J Neurogastroenterol Motil       Date:  2021-01-30       Impact factor: 4.924

2.  A laparoscopic one anastomosis gastric bypass with wrapping versus nonwrapping fundus of the excluded part of the stomach to treat obese patients (FundoRingOAGB trial): study protocol for a randomized controlled trial.

Authors:  Oral Ospanov; Galymzhan Yeleuov; Alexandr Fursov; Bakhtiyar Yelembayev; Roman Fursov; Zhenis Sergazin; Adil Mustafin
Journal:  Trials       Date:  2022-04-07       Impact factor: 2.279

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.