Nayan Huang1,2, Wenjie Li1, Xiangjiang Rong3, Mei Champ4, Lian Wei5, Mo Li1, Haiyan Mu1, Yueqing Hu1, Zongjuan Ma1, Jihui Lyu1,2. 1. Center for Cognitive Disorders, Beijing Geriatric Hospital, Beijing, China. 2. Center for Brain Disorders Research, Capital Medical University; Beijing Institute of Brain Disorders, Beijing, China. 3. School of Kinesiology and Health, Capital University of Physical Education and Sport, Beijing, China. 4. Department of Nursing and Midwifery, University of the West of England, Bristol, UK. 5. Graduate School, Capital University of Physical Education and Sport, Beijing, China.
Abstract
BACKGROUND:Tai Chi exercise is a non-pharmacological therapy that has received increased attention in recent years. A Tai Chi program has been specifically modified for older people with cognitive impairments by the research team. OBJECTIVE: We aim to assess the effects of this Tai Chi program on mild dementia. METHODS:Eighty older people with mild dementia were recruited and randomly assigned to a Tai Chi group or a control group. The Tai Chi group practiced the Tai Chi program three times a week for 10 months, while the control group continued receiving routine treatments. All participants were assessed for cognitive function, behavior/mood, and activities of daily living at baseline, 5 months, and 10 months. RESULTS: The Tai Chi group performed better than the control group. Repeated measures ANOVA revealed a significant group×time interaction in the Montreal Cognitive Assessment (MoCA). Further analysis of sub-items of the MoCA showed a significant time effect in naming and abstraction. It was statistically significant in both main effect of time and group×time interaction in the Neuropsychiatric Inventory (NPI) and Geriatric Depression Scale (GDS). Paired sample t test showed the Tai Chi group scored lower at 5 and 10 months in the NPI and at 10 months in the GDS compared with baseline. The Tai Chi group scored lower than the control group at 10 months in the NPI and GDS. CONCLUSION: The results suggest this Tai Chi program may help improve cognitive function and mental well-being for older adults with mild dementia.
RCT Entities:
BACKGROUND: Tai Chi exercise is a non-pharmacological therapy that has received increased attention in recent years. A Tai Chi program has been specifically modified for older people with cognitive impairments by the research team. OBJECTIVE: We aim to assess the effects of this Tai Chi program on mild dementia. METHODS: Eighty older people with mild dementia were recruited and randomly assigned to a Tai Chi group or a control group. The Tai Chi group practiced the Tai Chi program three times a week for 10 months, while the control group continued receiving routine treatments. All participants were assessed for cognitive function, behavior/mood, and activities of daily living at baseline, 5 months, and 10 months. RESULTS: The Tai Chi group performed better than the control group. Repeated measures ANOVA revealed a significant group×time interaction in the Montreal Cognitive Assessment (MoCA). Further analysis of sub-items of the MoCA showed a significant time effect in naming and abstraction. It was statistically significant in both main effect of time and group×time interaction in the Neuropsychiatric Inventory (NPI) and Geriatric Depression Scale (GDS). Paired sample t test showed the Tai Chi group scored lower at 5 and 10 months in the NPI and at 10 months in the GDS compared with baseline. The Tai Chi group scored lower than the control group at 10 months in the NPI and GDS. CONCLUSION: The results suggest this Tai Chi program may help improve cognitive function and mental well-being for older adults with mild dementia.
Entities:
Keywords:
Behavioral and psychological symptoms; Tai Chi; cognitive function; dementia; depressive mood
Authors: Jennifer A Watt; Zahra Goodarzi; Areti Angeliki Veroniki; Vera Nincic; Paul A Khan; Marco Ghassemi; Yonda Lai; Victoria Treister; Yuan Thompson; Raphael Schneider; Andrea C Tricco; Sharon E Straus Journal: BMJ Date: 2021-03-24
Authors: Kathrin Steichele; Anne Keefer; Nikolas Dietzel; Elmar Graessel; Hans-Ulrich Prokosch; Peter L Kolominsky-Rabas Journal: Alzheimers Res Ther Date: 2022-07-22 Impact factor: 8.823