Literature DB >> 31742050

Role of Intraoperative Cytology in Head and Neck Lesions: A Prospective Study.

Florida Sharin1, Vipin R Ekhar1, Ritesh N Shelkar1, Jeevan N Vedi1.   

Abstract

To study the technique of intra-operative imprint cytology for intraoprative diagnosis and management in cases of Head and Neck malignant lesions and to compare its result with postoperative histopathology. Prospective study conducted over 2 yrs period at the Department of ENT of a tertiary care centre in central India. A total of 60 patients who were operated for Head and Neck malignant lesions were studies with regards to intraoperative diagnosis, marginal status and lymphnodal status and compared with postoperative histopathology. Mean age-group was 47.70 (± 13.7) years. There was male preponderance. Bucco-aveolar complex lesions constituted the majority followed by Tongue and thyroid lesions. Intraoperative cytology technique showed a sensitivity of 92.98%, 80.60% and 92.30% as regards the intraoperative diagnosis, marginal clearance and nodal metastases respectively; while the specificity was 100%, 90.09% and 83.33% respectively. At the end of the study we conclude that intra-operative cytology is a good technique for intra-operative evaluation in Head and Neck lesions, where facilities for frozen section are not available. It can be used as a simple, non-expensive and rapid alternative to frozen section. A larger and longer study can validate its routine use in surgical setups where high-end pathology setup is not available. © Association of Otolaryngologists of India 2018.

Entities:  

Keywords:  Frozen section; Head and neck malignancy; Intraoperative cytology; Marginal clearance; Nodal metastases

Year:  2018        PMID: 31742050      PMCID: PMC6848450          DOI: 10.1007/s12070-018-1519-9

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  12 in total

1.  Intraoperative analysis of sentinel lymph nodes by imprint cytology for cancer of the breast.

Authors:  Stephen A Shiver; Andrew J Creager; Kim Geisinger; Nancy D Perrier; Perry Shen; Edward A Levine
Journal:  Am J Surg       Date:  2002-11       Impact factor: 2.565

2.  Utility of rapid staining of fine needle aspiration smears at the University Hospital of the West Indies.

Authors:  S E Shirley; C T Escoffery; M Reid; K K Hay; M Sutherland; J Gray
Journal:  West Indian Med J       Date:  2003-03       Impact factor: 0.171

3.  Intraoperative sentinel lymph node examination by imprint cytology during breast surgery.

Authors:  G Baitchev; G Gortchev; A Todorova
Journal:  Curr Med Res Opin       Date:  2002       Impact factor: 2.580

4.  Role of imprint cytology in intraoperative diagnosis: value and limitations.

Authors:  K C Suen; W S Wood; A A Syed; N F Quenville; P B Clement
Journal:  J Clin Pathol       Date:  1978-04       Impact factor: 3.411

5.  Reliability of intraoperative frozen section and imprint cytological investigation of sentinel lymph nodes in breast cancer.

Authors:  P J Van Diest; H Torrenga; P J Borgstein; R Pijpers; R P Bleichrodt; F D Rahusen; S Meijer
Journal:  Histopathology       Date:  1999-07       Impact factor: 5.087

6.  A comparison of touch imprint cytology and Mohs frozen-section histology in the evaluation of Mohs micrographic surgical margins.

Authors:  S R Florell; L J Layfield; J W Gerwels
Journal:  J Am Acad Dermatol       Date:  2001-04       Impact factor: 11.527

7.  Using imprint and frozen sections in determining the surgical strategies for thyroid pathologies.

Authors:  F Taneri; A Poyraz; B Salman; E Tekin; N Akyuerek; O Bayram; E Onuk
Journal:  Endocr Regul       Date:  2001-06

8.  Cytopathology in the post mortem room.

Authors:  E Walker; J J Going
Journal:  J Clin Pathol       Date:  1994-08       Impact factor: 3.411

9.  Intraoperative imprint evaluation of surgical margins in oral squamous cell carcinoma.

Authors:  Gatha Singh Yadav; Mandana Donoghue; David P Tauro; Ashutosh Yadav; Sumit Agarwal
Journal:  Acta Cytol       Date:  2012-12-06       Impact factor: 2.319

10.  Comparison of three different staining techniques for intraoperative assessment of nodal metastasis in breast cancer.

Authors:  Mona Anand; Rajive Kumar; Paresh Jain; Sonal Asthana; S V S Deo; N K Shukla; Asis Karak
Journal:  Diagn Cytopathol       Date:  2004-12       Impact factor: 1.582

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.