Literature DB >> 31742042

Laryngopharyngeal Reflux and GERD: Correlation Between Reflux Symptom Index and Reflux Finding Score.

C Shilpa1, S Sandeep1, Swathi Chandresh1, Akash Grampurohit1, T Shivaram Shetty1.   

Abstract

To study the relationship between laryngopharyngeal reflux (LPR) and gastroesophageal reflux disease (GERD) using clinical scoring and endoscopy. Data was collected from a sample of 100 patients with GERD symptoms who presented to ENT out-patient department, for a duration of 2 years. Patients were evaluated using Reflux Symptom Index (RSI) questionnaire and Reflux Finding Score (RFS). All patients underwent videolaryngoscopy and upper gastrointestinal endoscopy. Patient with positive findings underwent treatment with proton pump inhibitors and were followed up for 3 months. Out of 100 patients, 23 had LPR, 19 had GERD, 40 had LPR + GERD, 18 were normal. Among the LPR group, the predominant symptoms were hoarseness of voice, globus sensation and heartburn. Majority of GERD group had globus sensation, dysphagia and heartburn as their predominant symptoms. On laryngoscopy, in both LPR and LPR + GERD group, most common finding was interarytenoid erythema and vocal cord edema. On esophagogastroduodenoscopy, in both GERD and LPR + GERD group, esophagitis was the most common finding. RSI value was highest in patients with LPR + GERD. RFS value was high in LPR group followed by groups of LPR + GERD and GERD. RSI and RFS are easily administered, highly reproducible, low cost clinical scoring symptom questionnaire which can identify the patients with LPR. 82.6% of LPR patients had significant RFS scoring but with no significant findings in OGD. This study also illustrates the importance of PPI therapy in LPR patients with no evidence of GERD. © Association of Otolaryngologists of India 2018.

Entities:  

Keywords:  Gastroesophageal reflux disease; Laryngopharyngeal reflux; Reflux Finding Score; Reflux Symptom Index

Year:  2018        PMID: 31742042      PMCID: PMC6848732          DOI: 10.1007/s12070-018-1480-7

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  8 in total

1.  Comparison of inter- and intraobserver consistency for grading of esophagitis by expert and trainee endoscopists.

Authors:  John E Pandolfino; Nimish B Vakil; Peter J Kahrilas
Journal:  Gastrointest Endosc       Date:  2002-11       Impact factor: 9.427

2.  Laryngeal pseudosulcus as a predictor of laryngopharyngeal reflux.

Authors:  C Hickson; C B Simpson; R Falcon
Journal:  Laryngoscope       Date:  2001-10       Impact factor: 3.325

3.  The association between Helicobacter pylori and laryngopharyngeal reflux in laryngeal pathologies.

Authors:  Engin Cekin; Mustafa Ozyurt; Evren Erkul; Koray Ergunay; Hakan Cincik; Burak Kapucu; Atila Gungor
Journal:  Ear Nose Throat J       Date:  2012-03       Impact factor: 1.697

4.  The validity and reliability of the reflux finding score (RFS).

Authors:  P C Belafsky; G N Postma; J A Koufman
Journal:  Laryngoscope       Date:  2001-08       Impact factor: 3.325

5.  Laryngeal examination is superior to endoscopy in the diagnosis of the laryngopharyngeal form of gastroesophageal reflux disease.

Authors:  Laimas Jonaitis; Ruta Pribuisiene; Limas Kupcinskas; Virgilijus Uloza
Journal:  Scand J Gastroenterol       Date:  2006-02       Impact factor: 2.423

Review 6.  The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury.

Authors:  J A Koufman
Journal:  Laryngoscope       Date:  1991-04       Impact factor: 3.325

7.  Symptoms, quality of life, videolaryngoscopy, and twenty-four-hour triple-probe pH monitoring in patients with typical and extraesophageal reflux.

Authors:  Eric S Powitzky; Leena Khaitan; C Gaelyn Garrett; William O Richards; Mark Courey
Journal:  Ann Otol Rhinol Laryngol       Date:  2003-10       Impact factor: 1.547

8.  Validity and reliability of the reflux symptom index (RSI).

Authors:  Peter C Belafsky; Gregory N Postma; James A Koufman
Journal:  J Voice       Date:  2002-06       Impact factor: 2.009

  8 in total

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