| Literature DB >> 31740104 |
Mario Bo1, Niccolò Marchionni2.
Abstract
Direct Oral Anticoagulants (DOACs) consistently demonstrated a greater net clinical benefit compared to Vitamin K Antagonists (VKAs) also in persons aged 75 years and over, who account for the largest proportion of AF patients; however, major uncertainties in DOACs prescription have to do with this age group. In this review, persistent uncertainties and implications of frailty and geriatric syndromes on DOACs prescription, and practical use of DOACs in real-world older persons, and will be discussed.Entities:
Keywords: Aged; Atrial fibrillation; Direct oral anticoagulants; Frail elderly
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Year: 2019 PMID: 31740104 DOI: 10.1016/j.ejim.2019.10.026
Source DB: PubMed Journal: Eur J Intern Med ISSN: 0953-6205 Impact factor: 4.487