Literature DB >> 31738639

Treatment algorithm for idiopathic sudden sensorineural hearing loss based on epidemiologic surveys of a large Japanese cohort.

Ryosuke Kitoh1, Shin-Ya Nishio1, Shin-Ichi Usami1.   

Abstract

Background: To date, there have been few conventional algorithms for the treatment of idiopathic sudden sensorineural hearing loss (SSNHL), as there have been only limited reports with high evidence levels.
Objectives: To propose an evidence- and trend-based treatment algorithm for SSNHL.
Methods: We referred not only to the evidence for each treatment, but also to trends related to treatment selection in Japan based on epidemiologic surveys, and considered the balance of the advantages and disadvantages with regard to each patient's condition.
Results: We propose an algorithm that begins with the grade of SSNHL severity as the prognosis of SSNHL is strongly related to the severity of hearing loss. We selected systemic corticosteroid therapy as the first-line therapy, and Intra-tympanic corticosteroid therapy as salvage therapy. We also proposed the use of prostaglandin E1 with corticosteroids for the treatment of SSNHL patients with severe hearing loss. According to the data obtained from an epidemiologic survey, we decided time limits for the application of each treatment.
Conclusion: An algorithm for the treatment for SSNHL is presented according to the results of epidemiologic surveys in Japan. It is expected that this algorithm can provide a guide to choosing the suitable treatment for SSNHL patients.

Entities:  

Keywords:  Sudden sensorineural hearing loss; algorithm; corticosteroids; epidemiological survey; intra-tympanic; prostaglandin E1

Year:  2019        PMID: 31738639     DOI: 10.1080/00016489.2019.1687936

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  3 in total

1.  Early hearing improvement predicts the prognosis of idiopathic sudden sensorineural hearing loss.

Authors:  Marie N Shimanuki; Seiichi Shinden; Naoki Oishi; Noriomi Suzuki; Kaho Iwabu; Tsubasa Kitama; Amina Kida; Koji Sakamoto; Kaoru Ogawa
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-01-02       Impact factor: 2.503

2.  N-Acetylcysteine Combined With Dexamethasone Treatment Improves Sudden Sensorineural Hearing Loss and Attenuates Hair Cell Death Caused by ROS Stress.

Authors:  Xue Bai; Sen Chen; Kai Xu; Yuan Jin; Xun Niu; Le Xie; Yue Qiu; Xiao-Zhou Liu; Yu Sun
Journal:  Front Cell Dev Biol       Date:  2021-03-18

3.  Effects of oral N-acetylcysteine combined with oral prednisolone on idiopathic sudden sensorineural hearing loss.

Authors:  Shih-Lung Chen; Chia-Ying Ho; Shy-Chyi Chin
Journal:  Medicine (Baltimore)       Date:  2022-07-01       Impact factor: 1.817

  3 in total

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