Sarah E Boston1, Lucinda L van Stee2, Nicholas J Bacon3, David Szentimrey4, Barbara M Kirby5, Sebastiaan van Nimwegen2, Vincent A Wavreille6. 1. Surgical Oncology, VCA Canada, 404 Veterinary Emergency and Referral, Newmarket, Ontario, Canada. 2. Small Animal Surgery, Utrecht University, Utrecht, The Netherlands. 3. Oncologic & Soft Tissue Surgery, Fitzpatrick Referrals, Guidlford, Surrey, United Kingdom. 4. VCA Canada, Western Veterinary Specialist Centre, Calgary, Alberta, Canada. 5. Small Animal Surgery, University College Dublin, Dublin, Ireland. 6. Departmentof Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio.
Abstract
OBJECTIVE: To report outcomes after radical mandibulectomy in cats. STUDY DESIGN: Multi-institutional retrospective study. ANIMALS: Eight cats were included. METHODS: Medical records were searched for cats with confirmed oral neoplasia treated with radical mandibulectomy. Data collected included demographics, surgical procedure, histopathological diagnosis, postoperative management, and outcomes. RESULTS: Ages ranged from 8 to 17 years. All cats had 75% to 90% of the mandible removed and feeding tubes placed. Seven cats had squamous cell carcinoma, and one cat had a giant cell tumor. Six cats ate on their own postoperatively. Three cats had local recurrence and tumor-related died at 136 and 291 days. Six cats had no recurrence, with survival times of 156, 465, 608, and 1023 days, and two cats were still alive at 316 and 461 days after surgery. The three long-term survivors died of causes unrelated to oral neoplasia. One cat died at 156 days due to aspiration of food material. The overall estimated mean survival time was 712 days. CONCLUSION: After radical mandibulectomy, independent food intake was achieved in 6 of eight cats, and four cats lived longer than one year. CLINICAL SIGNIFICANCE: Radical mandibulectomy should be considered for the treatment of extensive oral neoplasia in cats. Successful long-term outcomes are possible with aggressive supportive care perioperatively.
OBJECTIVE: To report outcomes after radical mandibulectomy in cats. STUDY DESIGN: Multi-institutional retrospective study. ANIMALS: Eight cats were included. METHODS: Medical records were searched for cats with confirmed oral neoplasia treated with radical mandibulectomy. Data collected included demographics, surgical procedure, histopathological diagnosis, postoperative management, and outcomes. RESULTS: Ages ranged from 8 to 17 years. All cats had 75% to 90% of the mandible removed and feeding tubes placed. Seven cats had squamous cell carcinoma, and one cat had a giant cell tumor. Six cats ate on their own postoperatively. Three cats had local recurrence and tumor-related died at 136 and 291 days. Six cats had no recurrence, with survival times of 156, 465, 608, and 1023 days, and two cats were still alive at 316 and 461 days after surgery. The three long-term survivors died of causes unrelated to oral neoplasia. One cat died at 156 days due to aspiration of food material. The overall estimated mean survival time was 712 days. CONCLUSION: After radical mandibulectomy, independent food intake was achieved in 6 of eight cats, and four cats lived longer than one year. CLINICAL SIGNIFICANCE: Radical mandibulectomy should be considered for the treatment of extensive oral neoplasia in cats. Successful long-term outcomes are possible with aggressive supportive care perioperatively.
Authors: Leah H Ackerman; Carlos H de Mello Souza; Galaxia Cortés-Hinojosa; Marc E Salute; Alexa A Stephen; Elizabeth Anthony; Keijiro Shiomitsu; Rowan J Milner Journal: Can J Vet Res Date: 2022-01 Impact factor: 0.897