Literature DB >> 31736224

Prophylactic nipple-sparing mastectomy in young previvors: Examining decision-making, reconstructive outcomes, and patient satisfaction in BRCA+ patients under 30.

Ara A Salibian1, Jonathan M Bekisz1, Jordan D Frey1, Brooke Miller1, Mihye Choi1, Nolan S Karp1.   

Abstract

Bilateral prophylactic mastectomies (BPM) in young previvors with high-risk mutations are rising; however, little data on management, therapy timing, and outcomes exist. BRCA+ patients under 30 undergoing BPM from 2006 to 2018 were reviewed. Twenty-two patients aged 23-29 underwent mastectomy 4.2 years after genetic diagnosis. Twelve patients completed surveys, most often citing personal decisions (50%) for undergoing mastectomy and plastic surgeons' recommendations (83.3%) for reconstruction. About 73% of patients completely understood risks/benefits of mastectomy and 63.6% of reconstruction. Patients reported high BREAST-Q Satisfaction and Well-Being scores. Continued educational resource development will optimize shared decision-making in the reconstructive process.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  BRCA; nipple-sparing mastectomy; previvor; quality-of-life

Mesh:

Year:  2019        PMID: 31736224     DOI: 10.1111/tbj.13692

Source DB:  PubMed          Journal:  Breast J        ISSN: 1075-122X            Impact factor:   2.431


  2 in total

Review 1.  Nipple Sparing Mastectomy as a Risk-Reducing Procedure for BRCA-Mutated Patients.

Authors:  Nicola Rocco; Giacomo Montagna; Carmen Criscitiello; Maurizio Bruno Nava; Francesca Privitera; Wafa Taher; Antonio Gloria; Giuseppe Catanuto
Journal:  Genes (Basel)       Date:  2021-02-10       Impact factor: 4.096

Review 2.  Body Image in BRCA-Positive Young Women Following Bilateral Risk-Reducing Mastectomy: A Review of the Literature.

Authors:  Christa Torrisi
Journal:  Front Psychol       Date:  2021-12-16
  2 in total

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