Matthieu Delion1, Evelyne Klinger2, Florian Bernard1, Ghislaine Aubin3, Aram Ter Minassian4, Philippe Menei5. 1. Department of Neurosurgery, University Hospital of Angers, Angers, France. 2. French Institute for Research on Handicap (IFRH), France, EA4136, University of Bordeaux, Bordeaux, France. 3. Department of Neurology, University Hospital of Angers, Angers, France; Laboratoire de Psychologie des Pays de la Loire (LUNAM) UPRES EA 4638, University of Angers, Angers, France; Neuropsychological Unit, Department of Rehabilitation Medicine, Regional Centre for Functional Rehabilitation, Angers, France. 4. Department of Anesthesia, Critical Care and Emergency, University Hospital of Angers, Angers, France; Laboratoire Angevin de Recherche en Ingénierie des Systèmes (LARIS) EA 7315, Image Signal et Sciences du Vivant, University of Angers, Angers, France. 5. Department of Neurosurgery, University Hospital of Angers, Angers, France; Centre de Recherche en Cancérologie et Immunologie Nantes Angers (CRCINA), Institut National de la Santé et de la Recherche Médicale (INSERM), University of Nantes, University of Angers, Angers, France. Electronic address: phmenei@chu-angers.fr.
Abstract
BACKGROUND: Brain mapping by direct electrical stimulation during awake craniotomy is now a standard procedure that reduces the risk of permanent neurologic deficits. Virtual reality technology immerses the patient in a virtually controlled, interactive world, offering a unique opportunity to develop innovative tasks for perioperative mapping of complex cognitive functions. The objective of this prospective single-center study was to evaluate the tolerance and safety of a virtual reality headset (VRH) and immersive virtual experiences in patients undergoing awake craniotomy and brain mapping by direct electrical stimulation. METHODS: The study included 30 patients with a brain tumor near the language area. Language mapping was performed with a naming task, DO 80, presented on a digital tablet and then in two-dimensional and three-dimensional formats through a VRH. During wound closure, different virtual reality experiences were proposed to the patient, offering different types of virtual motion or interaction with an avatar piloted by a neuropsychologist. RESULTS: Two patients could not use the VRH owing to technical issues. No procedure was aborted, no patient experienced virtual reality sickness and all patients reported they would repeat the procedure. Despite a high rate of intraoperative focal seizures, there was no argument to attribute the seizures to VRH use. CONCLUSIONS: This study shows that it is possible during awake brain surgery to immerse the patient in a virtual environment and to interact with the patient, opening the field of new brain mapping procedures for complex cognitive functions.
BACKGROUND: Brain mapping by direct electrical stimulation during awake craniotomy is now a standard procedure that reduces the risk of permanent neurologic deficits. Virtual reality technology immerses the patient in a virtually controlled, interactive world, offering a unique opportunity to develop innovative tasks for perioperative mapping of complex cognitive functions. The objective of this prospective single-center study was to evaluate the tolerance and safety of a virtual reality headset (VRH) and immersive virtual experiences in patients undergoing awake craniotomy and brain mapping by direct electrical stimulation. METHODS: The study included 30 patients with a brain tumor near the language area. Language mapping was performed with a naming task, DO 80, presented on a digital tablet and then in two-dimensional and three-dimensional formats through a VRH. During wound closure, different virtual reality experiences were proposed to the patient, offering different types of virtual motion or interaction with an avatar piloted by a neuropsychologist. RESULTS: Two patients could not use the VRH owing to technical issues. No procedure was aborted, no patient experienced virtual reality sickness and all patients reported they would repeat the procedure. Despite a high rate of intraoperative focal seizures, there was no argument to attribute the seizures to VRH use. CONCLUSIONS: This study shows that it is possible during awake brain surgery to immerse the patient in a virtual environment and to interact with the patient, opening the field of new brain mapping procedures for complex cognitive functions.
Authors: Morgane Casanova; Anne Clavreul; Gwénaëlle Soulard; Matthieu Delion; Ghislaine Aubin; Aram Ter Minassian; Renaud Seguier; Philippe Menei Journal: J Med Internet Res Date: 2021-03-24 Impact factor: 5.428
Authors: Rakesh Mishra; M D Krishna Narayanan; Giuseppe E Umana; Nicola Montemurro; Bipin Chaurasia; Harsh Deora Journal: Int J Environ Res Public Health Date: 2022-02-02 Impact factor: 3.390
Authors: Thomas Roxburgh; Anthony Li; Charles Guenancia; Patrice Pernollet; Claire Bouleti; Benjamin Alos; Matthieu Gras; Thomas Kerforne; Denis Frasca; François Le Gal; Luc Christiaens; Bruno Degand; Rodrigue Garcia Journal: J Med Internet Res Date: 2021-05-27 Impact factor: 5.428