Literature DB >> 31734032

Racial differences in overdose events and polydrug detection in Indianapolis, Indiana.

Bradley Ray1, Evan Lowder2, Katie Bailey3, Philip Huynh3, Richard Benton4, Dennis Watson5.   

Abstract

BACKGROUND: We examine racial disparities in drug overdose death rates by analyzing trends in fatal and nonfatal overdose outcomes in a large metropolitan area (Indianapolis, Indiana).
METHODS: Death certificate and toxicology records for accidental drug overdose deaths from 2011 to 2018 were linked with emergency medical services (EMS) data. Bivariate comparisons examined differences in toxicology findings at the time of death as well as prior EMS events both overall and by indicator of non-fatal overdose.
RESULTS: From 2011-2018, 2204 residents (29.4 per 100,000) died of drug overdose, 18.6% were Black (N = 410, 19.5 per 100,000) and 78.5% White (N = 1730, 35.2 per 100,000). In the year prior to death, 33.5% (N = 656) of decedents had an EMS event, 12.1% (N = 237) had an overdose event, and 9.4% (N = 185) had naloxone administered. Overdose complaint and naloxone administration were more likely to occur among White than Black patients. White decedents were more likely than Black decedents to have had naloxone administered in the year prior to death (10.1% vs. 6.8%, χ2 = 4.0, p < .05, Cramer's V=.05). Toxicology data illustrate changing polydrug combinations, with Black decedents more likely to test positive for fentanyl-cocaine polydrug use in recent years.
CONCLUSIONS: Recent racial disparities in overdose deaths are driven by a combination of fentanyl and cocaine, which disproportionally impacts African American drug users, but may be addressed through expanded harm reduction and community outreach services. Additionally, there is a need to assess the role of differing practices in overdose emergency service provision as a contributing factor to disparities.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Fentanyl; Naloxone; Opioids; Overdose; Polydrug; Race

Year:  2019        PMID: 31734032     DOI: 10.1016/j.drugalcdep.2019.107658

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  5 in total

1.  Racial differences in overdose training, naloxone possession, and naloxone administration among clients and nonclients of a syringe services program.

Authors:  A A Jones; J N Park; S T Allen; K E Schneider; B W Weir; D Hunt; S G Sherman
Journal:  J Subst Abuse Treat       Date:  2021-04-15

2.  Characterizing opioid-involved overdose risk in local communities: An opioid overdose vulnerability assessment across Indiana, 2017.

Authors:  Jared L Sawyer; Shikhar Shrestha; Jennifer C Pustz; Robert Gottlieb; Deborah Nichols; Michelle Van Handel; Cailyn Lingwall; Thomas J Stopka
Journal:  Prev Med Rep       Date:  2021-08-27

3.  Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.

Authors:  Dennis P Watson; Tess Weathers; Alan McGuire; Alex Cohen; Philip Huynh; Clay Bowes; Daniel O'Donnell; Krista Brucker; Sumedha Gupta
Journal:  Drug Alcohol Depend       Date:  2021-02-15       Impact factor: 4.492

4.  Community overdose surveillance: Comparing substances collected from the death scene investigation to toxicology results.

Authors:  Tracy-Lynn E Lockwood; Philip Huynh; Alex Richard; Emily Sightes; Katie Bailey; Bradley Ray; Marya Lieberman
Journal:  Drug Alcohol Depend       Date:  2021-04-24       Impact factor: 4.852

5.  Impact of COVID-19 Pandemic on Drug Overdoses in Indianapolis.

Authors:  Nancy Glober; George Mohler; Philip Huynh; Tom Arkins; Dan O'Donnell; Jeremy Carter; Brad Ray
Journal:  J Urban Health       Date:  2020-10-01       Impact factor: 3.671

  5 in total

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