Literature DB >> 31732919

Impact of Free-Breathing Phase-Contrast MRI on Decision-Making in Fontan Surgical Planning.

Zhenglun Alan Wei1, Phillip M Trusty1, Yingnan Zhang1, Elaine Tang2, Kevin K Whitehead3, Mark A Fogel3, Ajit P Yoganathan4.   

Abstract

Fontan surgical planning ranks proposed surgical options according to their hemodynamics assessed by computational fluid dynamic (CFD) modeling. CFD commonly utilizes blood flow acquired under breath-holding (BH) conditions. Ignoring the free-breathing (FB) effect on blood flow waveforms may impact the ranking of surgical options. This study investigates such a potential impact by including ten Fontan patients who had blood flow acquisitions under both BH and FB conditions. A virtual surgery platform was used to generate two surgical options for each patient: (1) a traditional Fontan conduit and (2) a Y-graft. These options were ranked based on clinically relevant hemodynamic metrics: power loss (PL) and hepatic flow distribution (HFD). No difference was found in the ranking of options between using FB and BH flow acquisitions. The findings indicated that decision-making is not affected by the types of flow acquisition for Fontan surgical planning.

Entities:  

Keywords:  Computational fluid dynamics; Fontan surgical planning; Phase-contrast MRI

Year:  2019        PMID: 31732919     DOI: 10.1007/s12265-019-09930-0

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN: 1937-5387            Impact factor:   4.132


  4 in total

1.  Computational Investigation of Anastomosis Options of a Right-Heart Pump to Patient Specific Pulmonary Arteries.

Authors:  Nicolas Tobin; Bryan C Good; Jonathan D Plasencia; Mark A Fogel; William J Weiss; Keefe B Manning
Journal:  Ann Biomed Eng       Date:  2022-04-22       Impact factor: 3.934

2.  Non-Newtonian Effects on Patient-Specific Modeling of Fontan Hemodynamics.

Authors:  Zhenglun Wei; Shelly Singh-Gryzbon; Phillip M Trusty; Connor Huddleston; Yingnan Zhang; Mark A Fogel; Alessandro Veneziani; Ajit P Yoganathan
Journal:  Ann Biomed Eng       Date:  2020-05-05       Impact factor: 3.934

3.  Fluid-Structure Interaction Simulation of an Intra-Atrial Fontan Connection.

Authors:  Elaine Tang; Zhenglun Alan Wei; Mark A Fogel; Alessandro Veneziani; Ajit P Yoganathan
Journal:  Biology (Basel)       Date:  2020-11-24

4.  Is Doppler Echocardiography Adequate for Surgical Planning of Single Ventricle Patients?

Authors:  Zhenglun Alan Wei; Biao Si; Xiaoqian Ge; Meng Zhu; Maria A Cetatoiu; Chenze Tian; Lixin Sun; Bin Qiao
Journal:  Cardiovasc Eng Technol       Date:  2021-04-30       Impact factor: 2.495

  4 in total

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