Literature DB >> 31732792

Grey matter volume in developmental speech and language disorder.

Lauren Pigdon1,2, Catherine Willmott2,3, Sheena Reilly1,4, Gina Conti-Ramsden1,5, Christian Gaser6, Alan Connelly7,8, Angela T Morgan9,10,11.   

Abstract

Developmental language disorder (DLD) and developmental speech disorder (DSD) are common, yet their etiologies are not well understood. Atypical volume of the inferior and posterior language regions and striatum have been reported in DLD; however, variability in both methodology and study findings limits interpretations. Imaging research within DSD, on the other hand, is scarce. The present study compared grey matter volume in children with DLD, DSD, and typically developing speech and language. Compared to typically developing controls, children with DLD had larger volume in the right cerebellum, possibly associated with the procedural learning deficits that have been proposed in DLD. Children with DSD showed larger volume in the left inferior occipital lobe compared to controls, which may indicate a compensatory role of the visual processing regions due to sub-optimal auditory-perceptual processes. Overall, these findings suggest that different neural systems may be involved in the specific deficits related to DLD and DSD.

Entities:  

Keywords:  Child; Language; MRI; Speech; VBM

Mesh:

Year:  2019        PMID: 31732792     DOI: 10.1007/s00429-019-01978-7

Source DB:  PubMed          Journal:  Brain Struct Funct        ISSN: 1863-2653            Impact factor:   3.270


  3 in total

1.  The Effect of Abnormal Regional Homogeneity and Spontaneous Low-Frequency Brain Activity on Lower Cognitive Ability: A Cross-Sectional Study on Postoperative Children With Tetralogy of Fallot.

Authors:  Siyu Ma; Yuanli Hu; Yuting Liu; Yiwei Pu; Pengcheng Zuo; Qinghui Hu; Zhaocong Yang; Feng Chen; Zongyun Xie; Yueshuang Cun; Xiaoxu Liu; Ming Yang; Xuming Mo
Journal:  Front Neurosci       Date:  2022-02-07       Impact factor: 4.677

2.  Increased Gray Matter Volume Induced by Chinese Language Acquisition in Adult Alphabetic Language Speakers.

Authors:  Liu Tu; Fangyuan Zhou; Kei Omata; Wendi Li; Ruiwang Huang; Wei Gao; Zhenzhen Zhu; Yanyan Li; Chang Liu; Mengying Mao; Shuyu Zhang; Takashi Hanakawa
Journal:  Front Psychol       Date:  2022-04-25

3.  Quantitative MRI reveals differences in striatal myelin in children with DLD.

Authors:  Saloni Krishnan; Gabriel J Cler; Harriet J Smith; Hanna E Willis; Salomi S Asaridou; Máiréad P Healy; Daniel Papp; Kate E Watkins
Journal:  Elife       Date:  2022-09-27       Impact factor: 8.713

  3 in total

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