| Literature DB >> 31732688 |
Ana C Blanchard1, Lin Tang2, Manal Tadros3, Matthew Muller4, Theodore Spilker5, Valerie J Waters6, John J LiPuma5, Elizabeth Tullis7.
Abstract
This report describes transmission of a Burkholderia cenocepacia ET12 strain (ET12-Bc) at the Toronto Adult Cystic Fibrosis (CF) Centre occurring from 2008 to 2017. Epidemiological and genomic data from 11 patients with CF were evaluated. Isolates were analysed using whole genome sequencing (WGS). Epidemiological investigation and WGS analysis suggested nosocomial transmission, despite enhanced infection control precautions. This was associated with subsequent deaths in 10 patients. ET12-Bc positive patients are no longer cared for on the same unit as ET12-Bc negative patients. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: bacterial infection; clinical epidemiology; cystic fibrosis; infection control
Year: 2019 PMID: 31732688 DOI: 10.1136/thoraxjnl-2019-214098
Source DB: PubMed Journal: Thorax ISSN: 0040-6376 Impact factor: 9.139