Literature DB >> 31732688

Burkholderia cenocepacia ET12 transmission in adults with cystic fibrosis.

Ana C Blanchard1, Lin Tang2, Manal Tadros3, Matthew Muller4, Theodore Spilker5, Valerie J Waters6, John J LiPuma5, Elizabeth Tullis7.   

Abstract

This report describes transmission of a Burkholderia cenocepacia ET12 strain (ET12-Bc) at the Toronto Adult Cystic Fibrosis (CF) Centre occurring from 2008 to 2017. Epidemiological and genomic data from 11 patients with CF were evaluated. Isolates were analysed using whole genome sequencing (WGS). Epidemiological investigation and WGS analysis suggested nosocomial transmission, despite enhanced infection control precautions. This was associated with subsequent deaths in 10 patients. ET12-Bc positive patients are no longer cared for on the same unit as ET12-Bc negative patients. © Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  bacterial infection; clinical epidemiology; cystic fibrosis; infection control

Year:  2019        PMID: 31732688     DOI: 10.1136/thoraxjnl-2019-214098

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  2 in total

1.  Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules.

Authors:  Roberto Rosales-Reyes; Paola Garza-Villafuerte; Daniela Vences-Vences; Daniel F Aubert; Rubi Aca-Teutle; Vianney F Ortiz-Navarrete; Laura C Bonifaz; Julio Cesar Carrero-Sánchez; Alfonso Olivos-García; Miguel A Valvano; José Ignacio Santos-Preciado
Journal:  Emerg Microbes Infect       Date:  2020-12       Impact factor: 7.163

2.  Complete Genome Sequence of Burkholderia cenocepacia K56-2, an Opportunistic Pathogen.

Authors:  Inmaculada García-Romero; Miguel A Valvano
Journal:  Microbiol Resour Announc       Date:  2020-10-22
  2 in total

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