| Literature DB >> 31732598 |
Amit Kj Mandal1, Bashir Mohamad1, Constantinos G Missouris2.
Abstract
Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as 'micrococci', subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.Entities:
Keywords: Osler; Streptococcus pneumoniae; endocarditis; splenectomy
Year: 2019 PMID: 31732598 PMCID: PMC6899236 DOI: 10.7861/clinmed.2019.0253
Source DB: PubMed Journal: Clin Med (Lond) ISSN: 1470-2118 Impact factor: 2.659