Literature DB >> 31732598

Lessons of the month 3: Gone but not forgotten - Osler - a reminder of the syndrome not bearing his name.

Amit Kj Mandal1, Bashir Mohamad1, Constantinos G Missouris2.   

Abstract

Streptococcus pneumoniae is the most frequently implicated microbial agent in community acquired bacterial pneumonia and meningitis. It is also responsible for between 1 and 3% of cases of native valve infective endocarditis, with mortality rates up to 60%. Osler first described the association between pneumococcal pneumonia, endocarditis, and meningitis secondary to bacteria that he described as 'micrococci', subsequently elucidated to be S pneumoniae by Robert Austrian, and the syndrome bears his name. We report a case of fulminant pneumococcal native aortic valve endocarditis and perforation in a young male patient with chronic alcoholism and splenectomy who exhibited poor compliance to pneumococcal prophylaxis.
© 2019 Royal College of Physicians.

Entities:  

Keywords:  Osler; Streptococcus pneumoniae; endocarditis; splenectomy

Year:  2019        PMID: 31732598      PMCID: PMC6899236          DOI: 10.7861/clinmed.2019.0253

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  4 in total

1.  Pneumococcal endocarditis, meningitis, and rupture of the aortic valve.

Authors:  R AUSTRIAN
Journal:  AMA Arch Intern Med       Date:  1957-04

Review 2.  Austrian syndrome: report of two new cases and literature review.

Authors:  Carlos Gonzalez-Juanatey; Ana Testa; Jose Mayo; Miguel A Gonzalez-Gay
Journal:  Int J Cardiol       Date:  2005-08-31       Impact factor: 4.164

3.  Review of pneumococcal endocarditis in adults in the penicillin era.

Authors:  S I Aronin; S K Mukherjee; J C West; E L Cooney
Journal:  Clin Infect Dis       Date:  1998-01       Impact factor: 9.079

4.  Pneumococcal bacteraemia: 325 episodes diagnosed at St Thomas's Hospital.

Authors:  W R Gransden; S J Eykyn; I Phillips
Journal:  Br Med J (Clin Res Ed)       Date:  1985-02-16
  4 in total
  1 in total

1.  Austrian syndrome.

Authors:  Christian Schandl
Journal:  Clin Med (Lond)       Date:  2020-03       Impact factor: 2.659

  1 in total

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