Literature DB >> 31730775

Advances in immunomodulatory therapy for severe acute pancreatitis.

Fahad Munir1, Muhammad Babar Jamshed2, Numan Shahid3, Hajar Mansoor Hussain2, Syed Aun Muhammad4, Abdullah Al Mamun5, QiYu Zhang6.   

Abstract

Severe acute pancreatitis (SAP) has a complex course and a worse prognosis. Immune response imbalance is an important cause of severe pancreatitis or even death in patients. Immunomodulation therapy can regulate the imbalance of inflammatory response, alleviate SAP-related organ damage and improve the prognosis of patients. There are some problems in early immune regulation measures, such as single target and simple way. In recent years, new treatment methods, such as regulating the maturation and apoptosis of immune cells, the application of mesenchymal stem cells (MSCs) and multifactor combination therapy, have provided new ideas and hope for the future treatment of SAP. This article reviews the development of SAP immunoregulation and its recent progress.
Copyright © 2019 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Immune regulation; Immune response; Inflammatory response; Severe acute pancreatitis

Year:  2019        PMID： 31730775     DOI： 10.1016/j.imlet.2019.11.002

Source DB:  PubMed          Journal:  Immunol Lett        ISSN： 0165-2478            Impact factor:   3.685


  7 in total

1.  Influence of Intestinal Lymphatic Ligation on Pulmonary Injury in Rats with Severe Acute Pancreatitis.

Authors:  Yuan-Qi Liu; Lu-Lu Wang; Li Chen; Yu-Xia Xiong
Journal:  Curr Med Sci       Date:  2022-08-13

2.  Dynamic Monitoring of Immunoinflammatory Response Identifies Immunoswitching Characteristics of Severe Acute Pancreatitis in Rats.

Authors:  Qian Zhuang; Liqiang Huang; Yue Zeng; Xu Wu; Gan Qiao; Minghua Liu; Lulu Wang; Yejiang Zhou; Yuxia Xiong
Journal:  Front Immunol       Date:  2022-05-19       Impact factor: 8.786

3.  Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial.

Authors:  Lu Ke; Jing Zhou; Wenjian Mao; Tao Chen; Yin Zhu; Xinting Pan; Hong Mei; Vikesh Singh; James Buxbaum; Gordon Doig; Chengjian He; Weili Gu; Weihua Lu; Shumin Tu; Haibin Ni; Guoxiu Zhang; Xiangyang Zhao; Junli Sun; Weiwei Chen; Jingchun Song; Min Shao; Jianfeng Tu; Liang Xia; Wenhua He; Qingyun Zhu; Kang Li; Hongyi Yao; Jingyi Wu; Long Fu; Wendi Jiang; He Zhang; Jiajia Lin; Baiqiang Li; Zhihui Tong; John Windsor; Yuxiu Liu; Weiqin Li
Journal:  Intensive Care Med       Date:  2022-06-17       Impact factor: 41.787

4.  ATF4-mediated histone deacetylase HDAC1 promotes the progression of acute pancreatitis.

Authors:  Xiaofeng Deng; Yu He; Xiongying Miao; Bo Yu
Journal:  Cell Death Dis       Date:  2021-01-04       Impact factor: 8.469

5.  Effectiveness and safety of Liuhedan for treating acute pancreatitis: A protocol for systematic review and meta analysis.

Authors:  Tao Cheng; Bo-Fu Liu; Tian-Yong Han; Zhi-Han Gu; Pan Pan; Yu Haifang
Journal:  Medicine (Baltimore)       Date:  2021-02-26       Impact factor: 1.817

6.  Trajectories of Lymphocyte Counts in the Early Phase of Acute Pancreatitis Are Associated With Infected Pancreatic Necrosis.

Authors:  Jing Zhou; Wensong Chen; Yang Liu; Cheng Qu; Wendi Jiang; Jiangtao Yin; Jiajia Lin; Wenjian Mao; Bo Ye; Jing Zhou; Lu Ke; Zhihui Tong; Yuxiu Liu; Weiqin Li
Journal:  Clin Transl Gastroenterol       Date:  2021-09-22       Impact factor: 4.488

7.  Immune Dysfunction is Associated with Readmission in Survivors of Sepsis Following Infected Pancreatic Necrosis.

Authors:  Jiangtao Yin; Wenjian Mao; Xiaojia Xiao; Xianqiang Yu; Baiqiang Li; Faxi Chen; Jiajia Lin; Jing Zhou; Jing Zhou; Zhihui Tong; Lu Ke; Weiqin Li
Journal:  J Inflamm Res       Date:  2021-10-20
  7 in total

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