Literature DB >> 31730525

Omics-based biomarkers in the diagnosis of diabetes.

Wei Zien Gan1, Valsala Ramachandran1, Crystale Siew Ying Lim2, Rhun Yian Koh3.   

Abstract

Diabetes mellitus (DM) is a group of metabolic diseases related to the dysfunction of insulin, causing hyperglycaemia and life-threatening complications. Current early screening and diagnostic tests for DM are based on changes in glucose levels and autoantibody detection. This review evaluates recent studies on biomarker candidates in diagnosing type 1, type 2 and gestational DM based on omics classification, whilst highlighting the relationship of these biomarkers with the development of diabetes, diagnostic accuracy, challenges and future prospects. In addition, it also focuses on possible non-invasive biomarker candidates besides common blood biomarkers.

Entities:  

Keywords:  biomarkers; diabetes; gestational diabetes mellitus; omics; type 1 diabetes; type 2 diabetes

Mesh：

Substances：

Year:  2019        PMID： 31730525     DOI： 10.1515/jbcpp-2019-0120

Source DB:  PubMed          Journal:  J Basic Clin Physiol Pharmacol        ISSN： 0792-6855


  7 in total

Review 1.  Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer.

Authors:  Rajeswari Raguraman; Akhil Srivastava; Anupama Munshi; Rajagopal Ramesh
Journal:  Adv Drug Deliv Rev       Date:  2021-08-08       Impact factor: 15.470

2.  Systematic Review of Multi-Omics Approaches to Investigate Toxicological Effects in Macrophages.

Authors:  Isabel Karkossa; Stefanie Raps; Martin von Bergen; Kristin Schubert
Journal:  Int J Mol Sci       Date:  2020-12-09       Impact factor: 5.923

Review 3.  Circulating Nucleic Acid-Based Biomarkers of Type 2 Diabetes.

Authors:  Felipe Padilla-Martinez; Gladys Wojciechowska; Lukasz Szczerbinski; Adam Kretowski
Journal:  Int J Mol Sci       Date:  2021-12-28       Impact factor: 5.923

4.  Plasma cytokines during pregnancy provide insight into the risk of diabetes in the gestational diabetes risk group.

Authors:  Aili Tagoma; Kadri Haller-Kikkatalo; Astrid Oras; Kristine Roos; Anne Kirss; Raivo Uibo
Journal:  J Diabetes Investig       Date:  2022-05-24       Impact factor: 3.681

Review 5.  Dysbiosis in the Development of Type I Diabetes and Associated Complications: From Mechanisms to Targeted Gut Microbes Manipulation Therapies.

Authors:  Gratiela Gradisteanu Pircalabioru; Nicolae Corcionivoschi; Ozan Gundogdu; Mariana-Carmen Chifiriuc; Luminita Gabriela Marutescu; Bogdan Ispas; Octavian Savu
Journal:  Int J Mol Sci       Date:  2021-03-09       Impact factor: 5.923

6.  Multi-Omics Characterization of Type 2 Diabetes Mellitus-Induced Cognitive Impairment in the db/db Mouse Model.

Authors:  Xiaoxuan Song; Zeyu Zhu; Xiaohang Qian; Xiaoli Liu; Shengdi Chen; Huidong Tang
Journal:  Molecules       Date:  2022-03-15       Impact factor: 4.411

Review 7.  Current Challenges and Future Perspectives of Renal Tubular Dysfunction in Diabetic Kidney Disease.

Authors:  Suyan Duan; Fang Lu; Dandan Song; Chengning Zhang; Bo Zhang; Changying Xing; Yanggang Yuan
Journal:  Front Endocrinol (Lausanne)       Date:  2021-06-10       Impact factor: 5.555
  7 in total

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