| Literature DB >> 31730340 |
Wataru Muramatsu1, Hisashi Yamamoto1.
Abstract
A tantalum-catalyzed solvent-free approach for the construction of amide bonds with 1-(trimethylsilyl)imidazole is developed, and the mild reaction conditions are applicable to a wide variety of electrophilic amino acid homologues. This approach delivers a new class of peptides in high yields without any epimerization.Entities:
Year: 2019 PMID： 31730340 DOI： 10.1021/jacs.9b08415
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419