Elisa Cainelli1,2, Deborah Lidia Di Giacomo3, Giulia Mantegazza4, Luca Vedovelli5, Jacopo Favaro3, Clementina Boniver3. 1. Department of Developmental Psychology and Socialization, University of Padova, Via Venezia 8, 35133, Padua, Italy. cainelli.elisa@gmail.com. 2. Paediatric Neurology and Neurophysiology Unit, Department of Women's and Children's Health, University Hospital of Padova, Padua, Italy. cainelli.elisa@gmail.com. 3. Paediatric Neurology and Neurophysiology Unit, Department of Women's and Children's Health, University Hospital of Padova, Padua, Italy. 4. Child Neuropsychiatry of ASST Monza Brianza, Monza, Italy. 5. Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padua, Italy.
Abstract
OBJECTIVE: The aim of this study was to evaluate the ability of the Mini-Mental State Pediatric Examinations (MMSPE) in the individuation of neuropsychological impairments. METHOD: MMSPE was administered to 60 children attending a primary or lower secondary school suffering from neurological diseases, admitted to our neuropsychology services. All children performed both a MMSPE examination and a neuropsychological evaluation. Results of neuropsychological evaluation and MMSPE were dichotomized. Positive predictive value (PPV), negative predictive value (NPV), and accuracy were also calculated. RESULTS: The diagnostic performance of MMSPE showed a good overall accuracy (0.83, CI 95% 0.64-0.91), NPV (0.81, CI 95% 0.73-1.00), PPV (0.87, CI 95% 0.68-0.94), specificity (0.91, CI 95% 0.81-1.00), sensitivity (0.74, CI 95% 0.57-0.90), and odds ratio of 28.5 (CI 95% 6.6-123), p < 0.001. CONCLUSIONS: MMSPE has a good prognostic ability in predicting neuropsychological problems in the context of different neurological pediatric diseases. We suggest that this instrument could greatly improve pediatric clinical practice in identifying high-risk children.
OBJECTIVE: The aim of this study was to evaluate the ability of the Mini-Mental State Pediatric Examinations (MMSPE) in the individuation of neuropsychological impairments. METHOD: MMSPE was administered to 60 children attending a primary or lower secondary school suffering from neurological diseases, admitted to our neuropsychology services. All children performed both a MMSPE examination and a neuropsychological evaluation. Results of neuropsychological evaluation and MMSPE were dichotomized. Positive predictive value (PPV), negative predictive value (NPV), and accuracy were also calculated. RESULTS: The diagnostic performance of MMSPE showed a good overall accuracy (0.83, CI 95% 0.64-0.91), NPV (0.81, CI 95% 0.73-1.00), PPV (0.87, CI 95% 0.68-0.94), specificity (0.91, CI 95% 0.81-1.00), sensitivity (0.74, CI 95% 0.57-0.90), and odds ratio of 28.5 (CI 95% 6.6-123), p < 0.001. CONCLUSIONS: MMSPE has a good prognostic ability in predicting neuropsychological problems in the context of different neurological pediatric diseases. We suggest that this instrument could greatly improve pediatric clinical practice in identifying high-risk children.
Authors: Sarah J Wilson; Sallie Baxendale; William Barr; Sherifa Hamed; John Langfitt; Séverine Samson; Masako Watanabe; Gus A Baker; Christoph Helmstaedter; Bruce P Hermann; Mary-Lou Smith Journal: Epilepsia Date: 2015-03-16 Impact factor: 5.864
Authors: E Portaccio; B Goretti; S Lori; V Zipoli; S Centorrino; A Ghezzi; F Patti; V Bianchi; G Comi; M Trojano; M P Amato Journal: Mult Scler Date: 2009-03-24 Impact factor: 6.312