Ying Yang1,2, Qianqiu Li3, Jing Mao2, Zongfu Mao1,4. 1. School of Health Sciences, Wuhan University, Wuhan, China. 2. School of Nursing, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China. 3. Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China. 4. Global Health Institute, Wuhan University, Wuhan, China.
Abstract
OBJECTIVES: Fatigue is an important yet ignored symptom of chronic obstructive pulmonary disease (COPD). However, there is a paucity of literature from China on fatigue and its association with health-related quality of life (HRQoL) among COPD patients. The purpose of this study was to (a) evaluate fatigue of COPD inpatients in China and (b) explore the association between fatigue and HRQoL. METHODS: This cross-sectional study recruited patients hospitalised for an acute exacerbation of COPD within one month from three general hospitals in central China. Disease severity, fatigue and HRQoL were assessed for all participants using COPD Assessment Test (CAT), 9-item Functional Assessment of Chronic Illness Therapy-Fatigue scale (FACIT-F) and 12-Item Short-Form Health Survey (SF-12v2). RESULTS: A total of 210 COPD patients participated in the study between April 2017 and January 2018, with an average age of 71.1 ± 12.2 years old. The overall prevalence of moderate to severe fatigue was 48.5%. A worse FACIT-F score was associated with worse CAT score (r = -0.74, P < 0.01; B = -0.70, P < 0.01) and worse SF-12v2 score (r = 0.77, P < 0.01; B = 0.66, P < 0.01). CONCLUSION: Almost half of the COPD patients experience moderate to severe fatigue. Patients with greater disease severity exhibited more severe fatigue and worse HRQoL. Fatigue symptom has a strongly negative effect on COPD patients' HRQoL, physical health and mental health. Health personnel is recommended to provide fatigue-related screening, counselling and health education, particularly for patients with moderate to severe COPD.
OBJECTIVES:Fatigue is an important yet ignored symptom of chronic obstructive pulmonary disease (COPD). However, there is a paucity of literature from China on fatigue and its association with health-related quality of life (HRQoL) among COPDpatients. The purpose of this study was to (a) evaluate fatigue of COPD inpatients in China and (b) explore the association between fatigue and HRQoL. METHODS: This cross-sectional study recruited patients hospitalised for an acute exacerbation of COPD within one month from three general hospitals in central China. Disease severity, fatigue and HRQoL were assessed for all participants using COPD Assessment Test (CAT), 9-item Functional Assessment of Chronic Illness Therapy-Fatigue scale (FACIT-F) and 12-Item Short-Form Health Survey (SF-12v2). RESULTS: A total of 210 COPDpatients participated in the study between April 2017 and January 2018, with an average age of 71.1 ± 12.2 years old. The overall prevalence of moderate to severe fatigue was 48.5%. A worse FACIT-F score was associated with worse CAT score (r = -0.74, P < 0.01; B = -0.70, P < 0.01) and worse SF-12v2 score (r = 0.77, P < 0.01; B = 0.66, P < 0.01). CONCLUSION: Almost half of the COPDpatients experience moderate to severe fatigue. Patients with greater disease severity exhibited more severe fatigue and worse HRQoL. Fatigue symptom has a strongly negative effect on COPDpatients' HRQoL, physical health and mental health. Health personnel is recommended to provide fatigue-related screening, counselling and health education, particularly for patients with moderate to severe COPD.
Authors: John R Hurst; Mohd Kashif Siddiqui; Barinder Singh; Precil Varghese; Ulf Holmgren; Enrico de Nigris Journal: Int J Chron Obstruct Pulmon Dis Date: 2021-05-10