Fe3O4 nanoparticles coated with double imprinted polymers for magnetic solid phase extraction of lead(II) from biological and environmental samples.

Double imprinted polymer coated magnetic nanoparticles were fabricated with 4-nm size ZnO nanoparticles acting as the sacrifice templates, which were co-imprinted with template Pb(II) ions. After template removal, abundant transfer pores derived from ZnO nanoparticles were left around the selective adsorption sites derived from Pb(II) ions. The magnetic sorbent exhibit good selectivity, rapid adsorption kinetic and large adsorption capacity for Pb(II). They were used to extract trace Pb(II) followed by graphite furnace atomic absorption spectrometry detection. After the optimization of extraction conditions, following merits are found: (a) rapid extraction (10 min), (b) high preconcentration factor (100 fold), (c) sensitive detection with the detection limit of 9.4 ng·L-1, and (d) low relative standard deviation (6.9%) at a level of 50 ng·L-1 of Pb(II) analyzed 7 times. The method was employed in extraction and quantification of trace Pb in biological and environmental samples with satisfactory recoveries of 87.5-104%. Graphical abstractDouble imprinted polymer coated magnetic nanoparticles (MNPs@DIP) were fabricated and used for extraction of Pb(II) followed by graphite furnace atomic absorption spectrometry (GFAAS) detection. The method was successfully applied for the determination of Pb in environmental and biological samples.