Literature DB >> 31728627

Diagnosis of onychomycosis clinically by nail dermoscopy versus microbiological diagnosis.

Essam El-Din A Nada1, Moustafa A El Taieb2, Mohamed Ali El-Feky3,4, Hassan M Ibrahim5, Eisa M Hegazy5, Alaa E Mohamed5, Mostafa I El-Amir6.   

Abstract

Diagnosis of onychomycosis requires microbiological studies, which are time-consuming. Dermoscopy is non invasive, easy and coastless method. To evaluate the diagnostic role of dermoscopy in onychomycosis and comparing its findings with microbiological results. Eighty patients with onychomycosis and 40 controls were studied for nail dermoscopic finding, and microbiological examinations in the form of microscopic examination by 20% KOH, Sabouraud dextrose agar (SDA), and HiCrome Candida Differential Agar. 72.5% of the patients were females. Most of the patient were presented with one finger (35%) and two fingers (35%). 85% of the patient were presented clinically with distal lateral subungual onychomycosis followed by total dystrophic onychomycosis (12.5%) and lastly with superficial white onychomycosis (2.5%). 52.5% and 75% of the patients were positive by direct microscopic examination with 20%KOH and SDA, respectively. Dermatophytes isolated from 7.5% of the patient, non-dermatophytes (Aspergillus) was isolated from 2.5%, and 65% had Candida by SDA. C. albicans was the commonest species (75%), followed by C. tropicalis (17.3%), and lastly C. krusei (7.7%). Dermoscopic examinations of patients showed nail spikes, longitudinal striations, and color changes in 75%, 82.5%, and 95%, respectively, with statistically significant P value (P < 0.001). There was significant difference regarding long striations and yellow coloration dermoscopic finding with positive KOH patients. All patients with positive culture showed nail spikes on dermoscopic examination. Dermoscopy is a rapid tool for diagnosis of onychomycosis. Longitudinal striations is the best diagnostic dermoscopic finding. Microbiological test are still needed for accurate and reliable diagnosis.

Entities:  

Keywords:  Fungal culture; KOH; Nail dermoscopy; Onychomycosis

Year:  2019        PMID: 31728627     DOI: 10.1007/s00403-019-02008-6

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN: 0340-3696            Impact factor:   3.017


  7 in total

1.  Dermatoscopic Features of Onychomycosis and its Correlation with Nail Plate Potassium Hydroxide Mount (KOH), Culture, and Periodic Acid Schiff Stain (PAS) in North East India.

Authors:  Anita Marak; Shikha Verma; Wihiwot Valerie Lyngdoh; Biswajit Dey
Journal:  Indian J Dermatol       Date:  2021 Nov-Dec       Impact factor: 1.494

Review 2.  Dermoscopic Evaluation of Inflammatory Nail Disorders and Their Mimics.

Authors:  Sophie Soyeon Lim; Alex Chamberlain; Keunyoung Hur; Jungyoon Ohn; Byeol Han; Victoria Mar; Je-Ho Mun
Journal:  Acta Derm Venereol       Date:  2021-09-15       Impact factor: 3.875

Review 3.  Diagnosing Onychomycosis: What's New?

Authors:  Aditya K Gupta; Deanna C Hall; Elizabeth A Cooper; Mahmoud A Ghannoum
Journal:  J Fungi (Basel)       Date:  2022-04-29

4.  Prospective, comparative evaluation of a deep neural network and dermoscopy in the diagnosis of onychomycosis.

Authors:  Young Jae Kim; Seung Seog Han; Hee Joo Yang; Sung Eun Chang
Journal:  PLoS One       Date:  2020-06-11       Impact factor: 3.240

Review 5.  Dermoscopy for cutaneous fungal infections: A brief review.

Authors:  Sophie Soyeon Lim; Kihyuk Shin; Je-Ho Mun
Journal:  Health Sci Rep       Date:  2022-01-06

6.  Assessment of the Clinical Diagnosis of Onychomycosis by Dermoscopy.

Authors:  Yan Ma; Ying Ji; Wen Cen; Zusha Qiao; Yan Gao; Lu He; Wenli Feng
Journal:  Front Surg       Date:  2022-03-16

7.  Assessment of Visual Diagnosis by Podiatrists for HPV and Onychomycosis: The Need for Complementary Tests.

Authors:  Alberto Aldana-Caballero; Raquel Mayordomo; Félix Marcos-Tejedor
Journal:  J Fungi (Basel)       Date:  2022-01-29
  7 in total

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