| Literature DB >> 31728435 |
Tsuyoshi Uchida1, Hirochika Matsubara1, Yuuichirou Ohnuki1, Aya Sugimura1, Hiroyasu Matsuoka1, Tomofumi Ichihara1, Hiroyuki Nakajima1.
Abstract
Ciliated muconodular papillary tumors (CMPTs) of the lung have been recently characterized as low-grade malignant tumors and may be indistinguishable from adenocarcinoma in situ (AIS) because they are both abundant in mucous and spread along the alveolar walls. Herein, we report a case of CMPT with polymyalgia rheumatica (PMR)-like symptoms, which resolved after resection. After the surgery, antinuclear antibody tests were performed, but no abnormalities were noted. Furthermore, the lung tumor could not be distinguished from AIS, as revealed by a pathological examination. This case demonstrates two key points: the paraneoplastic symptoms of CMPT can indicate PMR, and it is difficult to diagnose peripheral lung tumors as CMPT unless there is a completely resected specimen available. The possibility exists that an increased number of older patients will be diagnosed with CMPT because of the increasing frequency of computed tomography performed in this population. Therefore, it is important for clinicians to obtain completely resected specimens to ensure accurate diagnosis and management of CMPT. 2019 AME Case Reports. All rights reserved.Entities:
Keywords: Adenocarcinoma in situ (AIS); ciliated muconodular papillary tumor (CMPT); differential diagnosis; paraneoplastic syndromes
Year: 2019 PMID: 31728435 PMCID: PMC6851452 DOI: 10.21037/acr.2019.09.06
Source DB: PubMed Journal: AME Case Rep ISSN: 2523-1995