Literature DB >> 31724505

Marine Actinomycetes-derived Natural Products.

Chengfang Yang1, Rui Qian1, Yao Xu1, Junxi Yi1, Yiwen Gu1, Xiaoyu Liu1, Haobing Yu1, Binghua Jiao1, Xiaoling Lu1, Wei Zhang2,3.   

Abstract

Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Keywords:  Antibacterial activity; Antiviral activity; Cytotoxic activity; Leadzzm321990compound; Marine actinomycetes; Secondary metabolites.

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Year:  2019        PMID: 31724505     DOI: 10.2174/1568026619666191114102359

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN: 1568-0266            Impact factor:   3.295


  2 in total

1.  Activation and discovery of tsukubarubicin from Streptomyces tsukubaensis through overexpressing SARPs.

Authors:  Qing-Bin Wu; Xin-Ai Chen; Zhong-Yuan Lv; Xiao-Ying Zhang; Yu Liu; Yong-Quan Li
Journal:  Appl Microbiol Biotechnol       Date:  2021-05-22       Impact factor: 4.813

2.  Mersaquinone, A New Tetracene Derivative from the Marine-Derived Streptomyces sp. EG1 Exhibiting Activity against Methicillin-Resistant Staphylococcus aureus (MRSA).

Authors:  Min Cheol Kim; Reiko Cullum; Ali M S Hebishy; Hala A Mohamed; Ahmed H I Faraag; Nehad M Salah; Mohamed S Abdelfattah; William Fenical
Journal:  Antibiotics (Basel)       Date:  2020-05-14
  2 in total

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