Sara Ivone Barros Morhy Terrazas1, Bryan Steve Martinez Galan1, Flávia Giolo De Carvalho2, Vinicius Paula Venancio3, Lusânia Maria Greggi Antunes3, Marcelo Papoti2, Maricely Janette Uria Toro4, Iuri Ferreira da Costa4, Ellen Cristini de Freitas5,6. 1. Department of Food and Nutrition. School of Pharmaceutical Sciences of Araraquara, State University of São Paulo, FCF UNESP, Rodovia Araraquara Jaú, km 01 s/n, Araraquara, São Paulo, 14800-903, Brazil. 2. School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, EEFERP/USP, Avenida do Café s/n, Ribeirão Preto, São Paulo, 14040-903, Brazil. 3. School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, FCFRP/USP, Avenida do Café s/n, Ribeirão Preto, São Paulo, 14040-903, Brazil. 4. Center of Natural Sciences and Technology, State University of Pará, UEPA, Travessa Dr. Enéas Pinheiro, no 2626, Belém, Pará, 66095-015, Brazil. 5. Department of Food and Nutrition. School of Pharmaceutical Sciences of Araraquara, State University of São Paulo, FCF UNESP, Rodovia Araraquara Jaú, km 01 s/n, Araraquara, São Paulo, 14800-903, Brazil. ellenfreitas@usp.br. 6. School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, EEFERP/USP, Avenida do Café s/n, Ribeirão Preto, São Paulo, 14040-903, Brazil. ellenfreitas@usp.br.
Abstract
PURPOSE: Açai pulp is a source of phytochemicals and has been associated with antioxidant, anti-inflammatory, and antigenotoxic effects. This study aimed to assess the effects of açai pulp consumption on oxidative, inflammatory, and aerobic capacity markers of cyclist athletes. RESEARCH METHODS AND PROCEDURES: A crossover, randomized, placebo-controlled, single-blind study was developed with ten male cyclists (33.5 ± 4.7 years old, body mass index of 23.9 ± 1.38 kg/m2, and training load around 1875 ± 238 AU/week). The athletes consumed 400 g/day of pasteurized açai pulp (AP) or placebo (PL) for 15 days, with a 30-day wash-out period between trials. Lipid peroxidation, serum antioxidant capacity, DNA damage in peripheral blood (Comet assay), IL-6and TNF-alpha, blood lactate concentration during effort, anaerobic threshold intensity (ATi), maximum workload reached (Wmax), rating of perceived exertion threshold (RPET), and heart rate threshold (HRT) were evaluated before and after each intervention. Data were analyzed using a linear regression model with mixed effects (p ≤ 0.05). RESULTS: Increased serum antioxidant capacity (p = 0.006) and decreased lipid peroxidation (p = 0.01) were observed in subjects after intervention with AP. Blood lactate levels during effort significantly decreased (by 29%, p = 0.025) and ATi increased (p = 0.006) after AP. No significant effect on DNA damage was attributed to AP consumption. CONCLUSION: We found notable effects of AP intervention on antioxidant status in athletes. Both the reduction in blood lactate concentration and increase in ATi during the effort suggest an overall improvement in the aerobic capacity of the cyclists, confirming that AP consumption may influence variables associated with performance in endurance athletes.
RCT Entities:
PURPOSE: Açai pulp is a source of phytochemicals and has been associated with antioxidant, anti-inflammatory, and antigenotoxic effects. This study aimed to assess the effects of açai pulp consumption on oxidative, inflammatory, and aerobic capacity markers of cyclist athletes. RESEARCH METHODS AND PROCEDURES: A crossover, randomized, placebo-controlled, single-blind study was developed with ten male cyclists (33.5 ± 4.7 years old, body mass index of 23.9 ± 1.38 kg/m2, and training load around 1875 ± 238 AU/week). The athletes consumed 400 g/day of pasteurized açai pulp (AP) or placebo (PL) for 15 days, with a 30-day wash-out period between trials. Lipid peroxidation, serum antioxidant capacity, DNA damage in peripheral blood (Comet assay), IL-6 and TNF-alpha, blood lactate concentration during effort, anaerobic threshold intensity (ATi), maximum workload reached (Wmax), rating of perceived exertion threshold (RPET), and heart rate threshold (HRT) were evaluated before and after each intervention. Data were analyzed using a linear regression model with mixed effects (p ≤ 0.05). RESULTS: Increased serum antioxidant capacity (p = 0.006) and decreased lipid peroxidation (p = 0.01) were observed in subjects after intervention with AP. Blood lactate levels during effort significantly decreased (by 29%, p = 0.025) and ATi increased (p = 0.006) after AP. No significant effect on DNA damage was attributed to AP consumption. CONCLUSION: We found notable effects of AP intervention on antioxidant status in athletes. Both the reduction in blood lactate concentration and increase in ATi during the effort suggest an overall improvement in the aerobic capacity of the cyclists, confirming that AP consumption may influence variables associated with performance in endurance athletes.
Entities:
Keywords:
Anthocyanins; Antioxidant; Athletes; Açai; DNA damage
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