Literature DB >> 31723510

Under-diagnosis of Takotsubo Cardiomyopathy Increases Risk of Adverse Events: A Case Study.

Harvinder S Power1.   

Abstract

Takotsubo cardiomyopathy (TC), or broken-heart syndrome, is characterized by high levels of adrenaline and noradrenaline leading to coronary artery vasospasm. Often presenting similarly to myocardial infarction (MI), Takotsubo is under-diagnosed in the population, typically leading to management under MI guidelines. An 80-year-old woman presented with chest pain and electrocardiogram (EKG or ECG) changes but on further investigations, it emerged that the underlying pathology was not consistent with MI. Here, we highlight the importance of considering alternative diagnoses even with an initially seemingly clear-cut picture of MI. Due to the nature of the pathology, management of Takotsubo under MI protocols can lead to worsened outcomes. It is therefore of importance to increasingly consider TC as a diagnosis in cases of unclear MI.
Copyright © 2019, Power et al.

Entities:  

Keywords:  cardiomyopathy; takosubo

Year:  2019        PMID: 31723510      PMCID: PMC6825445          DOI: 10.7759/cureus.5749

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  12 in total

Review 1.  Drug-Induced Takotsubo Cardiomyopathy.

Authors:  Kazuhiko Kido; Maya Guglin
Journal:  J Cardiovasc Pharmacol Ther       Date:  2017-05-11       Impact factor: 2.457

2.  N-terminal pro-brain natriuretic protein levels in takotsubo cardiomyopathy.

Authors:  Thanh Ha Nguyen; Christopher J Neil; Aaron L Sverdlov; Gnanadevan Mahadavan; Yuliy Y Chirkov; Angela M Kucia; Jeanette Stansborough; John F Beltrame; Joseph B Selvanayagam; Christopher J Zeitz; Allan D Struthers; Michael P Frenneaux; John D Horowitz
Journal:  Am J Cardiol       Date:  2011-08-24       Impact factor: 2.778

Review 3.  Takotsubo cardiomyopathy: a review.

Authors:  Mahdi Veillet-Chowdhury; Syed Fahad Hassan; Kathleen Stergiopoulos
Journal:  Acute Card Care       Date:  2014-03

4.  Consequences of misdiagnosis and mismanagement of Takotsubo cardiomyopathy.

Authors:  Chirayu Vyas; Sanjay Shah; Sameer Pancholy; Tejas Patel; Isam Moussa
Journal:  Acute Card Care       Date:  2012-12

5.  Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy.

Authors:  Christian Templin; Jelena R Ghadri; Johanna Diekmann; L Christian Napp; Dana R Bataiosu; Milosz Jaguszewski; Victoria L Cammann; Annahita Sarcon; Verena Geyer; Catharina A Neumann; Burkhardt Seifert; Jens Hellermann; Moritz Schwyzer; Katharina Eisenhardt; Josef Jenewein; Jennifer Franke; Hugo A Katus; Christof Burgdorf; Heribert Schunkert; Christian Moeller; Holger Thiele; Johann Bauersachs; Carsten Tschöpe; Heinz-Peter Schultheiss; Charles A Laney; Lawrence Rajan; Guido Michels; Roman Pfister; Christian Ukena; Michael Böhm; Raimund Erbel; Alessandro Cuneo; Karl-Heinz Kuck; Claudius Jacobshagen; Gerd Hasenfuss; Mahir Karakas; Wolfgang Koenig; Wolfgang Rottbauer; Samir M Said; Ruediger C Braun-Dullaeus; Florim Cuculi; Adrian Banning; Thomas A Fischer; Tuija Vasankari; K E Juhani Airaksinen; Marcin Fijalkowski; Andrzej Rynkiewicz; Maciej Pawlak; Grzegorz Opolski; Rafal Dworakowski; Philip MacCarthy; Christoph Kaiser; Stefan Osswald; Leonarda Galiuto; Filippo Crea; Wolfgang Dichtl; Wolfgang M Franz; Klaus Empen; Stephan B Felix; Clément Delmas; Olivier Lairez; Paul Erne; Jeroen J Bax; Ian Ford; Frank Ruschitzka; Abhiram Prasad; Thomas F Lüscher
Journal:  N Engl J Med       Date:  2015-09-03       Impact factor: 91.245

6.  High levels of circulating epinephrine trigger apical cardiodepression in a β2-adrenergic receptor/Gi-dependent manner: a new model of Takotsubo cardiomyopathy.

Authors:  Alexander R Lyon; Sian E Harding; Helen Paur; Peter T Wright; Markus B Sikkel; Matthew H Tranter; Catherine Mansfield; Peter O'Gara; Daniel J Stuckey; Viacheslav O Nikolaev; Ivan Diakonov; Laura Pannell; Haibin Gong; Hong Sun; Nicholas S Peters; Mario Petrou; Zhaolun Zheng; Julia Gorelik
Journal:  Circulation       Date:  2012-06-25       Impact factor: 29.690

7.  Stress-induced cardiomyopathy (Takotsubo)--broken heart and mind?

Authors:  Björn Redfors; Yangzhen Shao; Elmir Omerovic
Journal:  Vasc Health Risk Manag       Date:  2013-04-17

8.  Diagnosis of takotsubo cardiomyopathy is increasing over time in patients presenting as ST-elevation myocardial infarction.

Authors:  A M Otten; J P Ottervanger; T Symersky; H Suryapranata; M J de Boer; A H E M Maas
Journal:  Neth Heart J       Date:  2016-09       Impact factor: 2.380

Review 9.  Takotsubo cardiomyopathy: Pathophysiology and role of cardiac biomarkers in differential diagnosis.

Authors:  Prabhakaran Gopalakrishnan; Ramsha Zaidi; Muhammad Rizwan Sardar
Journal:  World J Cardiol       Date:  2017-09-26

Review 10.  Takotsubo cardiomyopathy a short review.

Authors:  Shahbaz Roshanzamir; Refai Showkathali
Journal:  Curr Cardiol Rev       Date:  2013-08
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