Sean Andrea 1,2 , Michael Papirny 3 , Thomas Raedler 3,4 Show Affiliations »
Abstract
OBJECTIVE: Despite the lack of clear guidelines, neuroimaging (computed tomography [CT] or magnetic resonance imaging [MRI]) is frequently performed in subjects presenting with first-episode psychosis (FEP). The objective of this study was to determine if the use of neuroimaging adds diagnostic yield in adolescents and young adults presenting with FEP. METHODS: The sample consisted of 443 subjects aged 15-24 with FEP (DSM-IV-TR and DSM-5) and no focal neurologic findings. Consecutive charts from January 1, 1998, to June 30, 2016, were reviewed retrospectively. A positive finding was defined as a result leading to urgent follow-up or intervention. RESULTS: Twenty-five (5.6%) of 443 subjects showed incidental findings unrelated to psychosis. The prevalence of positive findings from neuroimaging was 0%, indicating no diagnostic yield from neuroimaging. CONCLUSIONS: Routine neuroimaging did not provide diagnostic information leading to a change in clinical management and should not be recommended in the investigation of FEP. © Copyright 2019 Physicians Postgraduate Press, Inc.
OBJECTIVE: Despite the lack of clear guidelines, neuroimaging (computed tomography [CT] or magnetic resonance imaging [MRI]) is frequently performed in subjects presenting with first-episode psychosis (FEP). The objective of this study was to determine if the use of neuroimaging adds diagnostic yield in adolescents and young adults presenting with FEP. METHODS: The sample consisted of 443 subjects aged 15-24 with FEP (DSM-IV-TR and DSM-5) and no focal neurologic findings. Consecutive charts from January 1, 1998, to June 30, 2016, were reviewed retrospectively. A positive finding was defined as a result leading to urgent follow-up or intervention. RESULTS: Twenty-five (5.6%) of 443 subjects showed incidental findings unrelated to psychosis . The prevalence of positive findings from neuroimaging was 0%, indicating no diagnostic yield from neuroimaging. CONCLUSIONS: Routine neuroimaging did not provide diagnostic information leading to a change in clinical management and should not be recommended in the investigation of FEP. © Copyright 2019 Physicians Postgraduate Press, Inc.
Entities: Chemical
Disease
Mesh： See more »
Year: 2019
PMID： 31721483 DOI： 10.4088/JCP.18m12665
Source DB: PubMed Journal: J Clin Psychiatry ISSN： 0160-6689 Impact factor: 4.384