P Nau1, H T Jackson2, A Aryaie3, A Ibele4, D Shouhed5, E Lo Menzo6, M Kurian7, L Khaitan8. 1. Department of Surgery, Carver College of Medicine, Iowa City, IA, USA. 2. George Washington School of Medicine and Life Sciences, Washington, DC, USA. 3. Department of Surgery, Texas Tech, Lubbock, TX, USA. 4. University of Utah College of Medicine, Salt Lake City, UT, USA. 5. Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA. 6. Department of Surgery, Cleveland Clinic Florida, Weston, FL, USA. 7. New York University School of Medicine, New York, NY, USA. 8. Cleveland Medical Center, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH, 44106, USA. Leena.Khaitan@UHhospitals.org.
Abstract
BACKGROUND: Gastroesophageal reflux disease (GERD) affects two thirds of the American population. Obesity is also a disease that affects two thirds of the population. The pathophysiology of reflux disease is reasonably understood, however, the degree to which obesity affects this disease remains poorly defined. Therefore the approach to GERD in the obese patient requires special attention and its own algorithm. METHODS: A literature search was conducted to consolidate the current available literature on GERD and its management in the obese. In addition, the authors reviewed the literature and present expert opinion on controversial topics. RESULTS: It is well established that GERD is increased in obesity and the pathophysiology is reviewed. Management options for GERD are discussed, with a focus on the obese population. Management strategies including fundoplication and gastric bypass are discussed. In addition, bariatric surgery in the setting of GERD is also reviewed. CONCLUSIONS: Currently this is an extremely controversial topic and this white paper presents a strong review of the literature to help guide the management of this challenging disease in this population. Expert recommendations are given throughout the paper based upon the current available data.
BACKGROUND:Gastroesophageal reflux disease (GERD) affects two thirds of the American population. Obesity is also a disease that affects two thirds of the population. The pathophysiology of reflux disease is reasonably understood, however, the degree to which obesity affects this disease remains poorly defined. Therefore the approach to GERD in the obesepatient requires special attention and its own algorithm. METHODS: A literature search was conducted to consolidate the current available literature on GERD and its management in the obese. In addition, the authors reviewed the literature and present expert opinion on controversial topics. RESULTS: It is well established that GERD is increased in obesity and the pathophysiology is reviewed. Management options for GERD are discussed, with a focus on the obese population. Management strategies including fundoplication and gastric bypass are discussed. In addition, bariatric surgery in the setting of GERD is also reviewed. CONCLUSIONS: Currently this is an extremely controversial topic and this white paper presents a strong review of the literature to help guide the management of this challenging disease in this population. Expert recommendations are given throughout the paper based upon the current available data.
Entities:
Keywords:
Anti-reflux surgery in obesity; GERD; Obesity; Sleeve gastrectomy
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