| Literature DB >> 31720365 |
Fang Yu1, Michelle A Mathiason1, Kari Johnson2, Joseph E Gaugler3, Dan Klassen2.
Abstract
INTRODUCTION: Reminiscence therapy has been shown to improve mental health and quality of life in dementia; however, reminiscence therapy is often delivered by therapists instead of being technology-enabled. This study evaluated the preliminary efficacy of Memory Matters (MM), an iPad reminiscence game on mood, social interaction, quality of life, and behavioral and psychological symptoms of dementia.Entities:
Keywords: Dementia; Mood; Quality of life; Reminiscence; Social interaction
Year: 2019 PMID: 31720365 PMCID: PMC6838539 DOI: 10.1016/j.trci.2019.09.002
Source DB: PubMed Journal: Alzheimers Dement (N Y) ISSN: 2352-8737
Fig. 1Enrollment flow diagram.
Characteristics of the study sample
| All (N = 80) | Group MM (n = 32) | Individual MM (n = 32) | Control (n = 16) | ||
|---|---|---|---|---|---|
| Sex | .794 | ||||
| Male | 34 (43%) | 15 (47%) | 13 (41%) | 6 (38%) | |
| Female | 46 (58%) | 17 (53%) | 19 (59%) | 10 (63%) | |
| Age (years) | 82.1 ± 7.8 (62–98) | 81.7 ± 7.7 (67–94) | 80.7 ± 7.0 (67–91) | 85.6 ± 10.0 (62–98) | .112 |
| Education (years) | 15.3 ± 3.3 (8–24) | 15.9 ± 3.8 (8–24) | 15.2 ± 2.97 (10–22) | 14.3 ± 2.7 (12–20) | .291 |
| Baseline MMSE | 17.5 ± 6.7 (6–29) | 16.1 ± 7.3 (6–29) | 18.6 ± 5.8 (6–28) | 18.3 ± 7.0 (6–29) | .280 |
NOTE. Number and frequency for categorical variables; mean ± SD (range) for continuous variable. Percentages may not sum to 100% due to rounding.
Abbreviations: MM, Memory Matters; MMSE, Mini–Mental State Examination.
Comparison of baseline descriptive statistics on outcomes among groups
| All (N = 80) | Group MM (n = 32) | Individual MM (n = 32) | Control (n = 16) | |
|---|---|---|---|---|
| Mood | ||||
| Apathetic | 11.7 ± 2.9 | 12.1 ± 3.2 | 11.5 ± 3.0 | 11.3 ± 1.9 |
| Content | 17.7 ± 4.7 | 16.7 ± 4.9 | 18.7 ± 4.1 | 17.7 ± 4.6 |
| Hostile | 14.0 ± 4.8 | 14.6 ± 4.9 | 13.2 ± 3.9 | 14.7 ± 5.8 |
| Sad | 6.6 ± 2.8 | 7.0 ± 3.3 | 6.0 ± 1.9 | 6.9 ± 3.0 |
| Spirited | 37.1 ± 9.7 | 36.8 ± 10.5 | 37.8 ± 9.7 | 36.2 ± 8.0 |
| QoL | 83.4 ± 18.4 | 80.3 ± 19.7 | 85.5 ± 18.2 | 85.5 ± 14.8 |
| Social interaction | 37.2 ± 14.6 | 34.9 ± 13.2 | 39.8 ± 14.8 | 36.3 ± 15.8 |
| BPSD | ||||
| Number | 3.7 ± 2.6 | 4.1 ± 2.5 | 3.1 ± 2.4 | 3.9 ± 2.9 |
| Severity | 5.6 ± 4.9 | 7.7 ± 6.2 | 5.5 ± 6.6 | 6.3 ± 5.7 |
| Caregiver distress | 6.5 ± 6.3 | 6.6 ± 4.6 | 4.5 ± 4.4 | 5.9 ± 5.9 |
NOTE. The numbers represent mean ± SD.
Abbreviations: MM, Memory Matters; BPSD: Behavioral and psychological symptoms of dementia; QoL, quality of life.
Group differences in outcome at 6 and 12 weeks
| 6 weeks | 12 weeks | |||
|---|---|---|---|---|
| Mean ± SD | Mean ± SD | |||
| Mood | ||||
| Apathetic | ||||
| Individual versus Group | −0.78 ± 0.65 | −1.19 (.23) | 0.26 ± 0.66 | 0.39 (.69) |
| Individual versus Control | −0.48 ± 0.74 | −0.65 (.52) | −1.32 ± 0.78 | −1.69 (.09) |
| Group versus Control | 0.30 ± 0.80 | 0.37 (.71) | −1.58 ± 0.81 | −1.95 (.051) |
| Contented | ||||
| Individual versus Group | 0.78 ± 0.88 | 0.89 (.37) | 0.65 ± 0.85 | 0.77 (.44) |
| Individual versus Control | 1.29 ± 1.06 | 1.22 (.22) | 1.50 ± 0.98 | 1.53 (.13) |
| Group versus Control | 0.50 ± 1.08 | 0.47 (.64) | 0.85 ± 1.04 | 0.82 (.41) |
| Hostile | ||||
| Individual versus Group | −0.78 ± 0.80 | −0.98 (.33) | −0.02 ± 0.84 | −0.02 (.98) |
| Individual versus Control | −0.70 ± 0.97 | −0.73 (.47) | −0.61 ± 1.02 | −0.60 (.55) |
| Group versus Control | 0.08 ± 0.98 | 0.08 (.94) | −0.59 ± 1.03 | −0.57 (.57) |
| Sad | ||||
| Individual versus Group | −0.73 ± 0.61 | −1.20 (.23) | −0.09 ± 0.60 | −0.16 (.87) |
| Individual versus Control | −1.03 ± 0.71 | −1.45 (.15) | −0.80 ± 0.69 | −1.16 (.25) |
| Group versus Control | −0.31 ± 0.73 | 0.42 (.67) | −0.71 ± 0.74 | −0.96 (.34) |
| Spirited | ||||
| Individual versus Group | 1.62 ± 1.54 | 1.05 (.29) | 0.97 ± 1.47 | 0.66 (.51) |
| Individual versus Control | 1.64 ± 1.86 | 0.88 (.38) | 2.32 ± 1.80 | 1.29 (.20) |
| Group versus Control | 0.02 ± 1.89 | 0.01 (.99) | 1.35 ± 1.84 | 0.74 (.46) |
| QoL | ||||
| Individual versus Group | −2.71 ± 5.04 | −0.54 (.59) | −3.57 ± 4.09 | −0.87 (.38) |
| Individual versus Control | −4.59 ± 5.61 | −0.82 (.41) | −1.12 ± 4.93 | −0.23 (.82) |
| Group versus Control | −1.88 ± 5.92 | 0.32 (.75) | 2.45 ± 5.03 | 0.49 (.63) |
| Social interaction | ||||
| Individual versus Group | 5.41 ± 2.27 | 2.38 (.017) | 1.43 ± 2.70 | 0.53 (.60) |
| Individual versus Control | 7.78 ± 2.75 | 2.84 (.005) | 1.20 ± 3.30 | 0.36 (.72) |
| Group versus Control | 2.37 ± 2.83 | 0.84 (.40) | −0.23 ± 3.35 | −0.07 (.95) |
| BPSD | ||||
| Number of BPSD | ||||
| Individual versus Group | 0.32 ± 0.47 | 0.67 (.50) | 0.18 ± 0.58 | 0.32 (.75) |
| Individual versus Control | 0.32 ± 0.57 | 0.56 (.58) | 0.74 ± 0.73 | 1.02 (.31) |
| Group versus Control | 0.00 ± 0.58 | 0.00 (.99) | 0.56 ± 0.73 | 0.76 (.45) |
| BPSD Severity | ||||
| Individual versus Group | 0.50 ± 0.85 | 0.59 (.56) | −0.06 ± 0.90 | −0.06 (.95) |
| Individual versus Control | 0.51 ± 0.99 | −0.52 (.60) | 1.00 ± 1.11 | 0.90 (.37) |
| Group versus Control | 0.01 ± 1.04 | 0.01 (.99) | 1.06 ± 1.14 | 0.93 (.35) |
| Caregiver distress | ||||
| Individual versus Group | 0.20 ± 1.23 | 0.16 (.87) | 0.26 ± 1.37 | 0.19 (.85) |
| Individual versus Control | −0.16 ± 1.46 | −0.11 (.91) | 0.93 ± 1.68 | 0.56 (.58) |
| Group versus Control | −0.36 ± 1.48 | −0.24 (.81) | 0.67 ± 1.66 | 0.40 (.69) |
NOTE. The analyses were adjusted by baseline values, age, education, gender, and cognition at the baseline.
Abbreviations: Individual, Intervention was delivered by the interventionist to the participants one-on-one; Group, Intervention was delivered by the interventionist in a group of participants; Control, Control group; BPSD, Behavioral and psychological symptoms of dementia; QoL, quality of life.
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