Literature DB >> 31719737

A clinical study to describe the corneal topographic pattern and estimation of the prevalence of keratoconus among diagnosed cases of vernal keratoconjunctivitis.

Radhika H Umale1, M A Khan2, P S Moulick3, Sandeep Gupta4, Sandeep Shankar5, Alok Sati5.   

Abstract

BACKGROUND: Association of keratoconus with vernal keratoconjunctivitis is well known, but there are few topographic studies describing actual prevalence especially in India where it is a common condition. There is also scarce literature on the topographic patterns and subclinical topographic anomalies in cases of vernal catarrh and their relationship with various subtypes. This study was conducted to estimate the prevalence of subclinical keratoconus among Indian subjects with vernal keratoconjunctivitis and describe the various topographic abnormalities which can help in screening for these cases.
METHODS: In the cross-sectional study conducted at a tertiary care center, 76 established cases of vernal keratoconjunctivitis were evaluated with placido disc-based videokeratography for topographic abnormalities and early keratoconus based on modified Rabinowitz-McDonnell criteria.
RESULTS: Seventeen (11.2%) eyes satisfied both the modified Rabinowitz-McDonnell criteria of keratoconus. Corneal topographic pattern analysis showed asymmetric bowtie with inferior steepening in 17.11% of the patients. None of these patients had clinical evidence of keratoconus.
CONCLUSIONS: The study showed 11.2% prevalence of keratoconus in patients suffering from vernal keratoconjunctivitis. The findings highlight the importance of using a simple placido disc-based corneal topography system for screening the patients with vernal keratoconjunctivitis for keratoconus. This can help in early detection and preventive intervention.
© 2018 Armed Forces Medical Services (AFMS).

Entities:  

Keywords:  Keratoconus; Vernal keratoconjunctivitis; Videokeratography

Year:  2018        PMID: 31719737      PMCID: PMC6838601          DOI: 10.1016/j.mjafi.2018.07.012

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  10 in total

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2.  Keratoconus in Asian eyes at a tertiary eye care facility.

Authors:  Jagjit S Saini; Vandana Saroha; P Singh; Jaspreet S Sukhija; Arun K Jain
Journal:  Clin Exp Optom       Date:  2004-03       Impact factor: 2.742

3.  Topographic corneal changes in patients with vernal keratoconjunctivitis.

Authors:  Paulo Elias Correa Dantas; Milton Ruiz Alves; Maria Cristina Nishiwaki-Dantas
Journal:  Arq Bras Oftalmol       Date:  2005-11-28       Impact factor: 0.872

4.  Incidence of keratoconus in subjects with vernal keratoconjunctivitis: a videokeratographic study.

Authors:  Y Totan; I F Hepşen; O Cekiç; A Gündüz; E Aydin
Journal:  Ophthalmology       Date:  2001-04       Impact factor: 12.079

5.  Keratocyte apoptosis associated with keratoconus.

Authors:  W J Kim; Y S Rabinowitz; D M Meisler; S E Wilson
Journal:  Exp Eye Res       Date:  1999-11       Impact factor: 3.467

6.  Incidence of keratoconus in spring catarrh.

Authors:  M D Khan; N Kundi; N Saeed; A Gulab; A F Nazeer
Journal:  Br J Ophthalmol       Date:  1988-01       Impact factor: 4.638

7.  Very Low Prevalence of Keratoconus in a Large Series of Vernal Keratoconjunctivitis Patients.

Authors:  Roberto Caputo; Francesco Versaci; Neri Pucci; Cinzia de Libero; Gioia Danti; Salvatore De Masi; Rita Mencucci; Elio Novembre; Bennie H Jeng
Journal:  Am J Ophthalmol       Date:  2016-09-14       Impact factor: 5.258

8.  Measure of keratoconus progression in patients with vernal keratoconjunctivitis using scanning slit topography.

Authors:  Mukesh Taneja; Jatin N Ashar; Anurag Mathur; Pravin K Vaddavalli; Varsha Rathi; Virender Sangwan; Somashiela Murthy
Journal:  Cont Lens Anterior Eye       Date:  2012-10-23       Impact factor: 3.077

9.  Ocular complications of severe vernal keratoconjunctivitis (VKC) in Yemen.

Authors:  Saleh A Al-Akily; Mahfouth A Bamashmus
Journal:  Saudi J Ophthalmol       Date:  2011-02-16

10.  Allergen-specific exposure associated with high immunoglobulin E and eye rubbing predisposes to progression of keratoconus.

Authors:  Rohit Shetty; Shraddha Sureka; Pallak Kusumgar; Swaminathan Sethu; Kanchan Sainani
Journal:  Indian J Ophthalmol       Date:  2017-05       Impact factor: 1.848

  10 in total

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