Literature DB >> 3171482

Autoantibodies to the constitutive 73-kD member of the hsp70 family of heat shock proteins in systemic lupus erythematosus.

S Minota1, B Cameron, W J Welch, J B Winfield.   

Abstract

Serum from patients with systemic lupus erythematosus (SLE) frequently contain IgM and IgG autoantibodies to the constitutively expressed 73-kD/pI 5.5 member of the hsp70 family of heat shock proteins, as determined by one-dimensional (SDS-PAGE) and two-dimensional (IEF/SDS-PAGE) immunoblotting, and by solid-phase SLE Ig immunoprecipitation experiments using hsp70 protein-specific mAbs as probes. Autoantibodies to hsp70 also were detected in a minority of sera from patients with other rheumatic or viral diseases, but not in normal sera. These data may provide additional insight into etiologic and pathophysiologic mechanisms in this and related autoimmune disorders.

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Year:  1988        PMID： 3171482      PMCID： PMC2189089          DOI： 10.1084/jem.168.4.1475

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  13 in total

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Journal:  Annu Rev Biochem       Date:  1986       Impact factor: 23.643

2.  High resolution two-dimensional electrophoresis of proteins.

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Journal:  J Biol Chem       Date:  1975-05-25       Impact factor: 5.157

3.  Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein.

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Journal:  Cell       Date:  1983-11       Impact factor: 41.582

Review 4.  Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine.

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Journal:  Adv Immunol       Date:  1982       Impact factor: 3.543

5.  IgG anti-lymphocyte antibodies in systemic lupus erythematosus react with surface molecules shared by peripheral T cells and a primitive T cell line.

Authors:  S Minota; J B Winfield
Journal:  J Immunol       Date:  1987-03-15       Impact factor: 5.422

6.  The 1982 revised criteria for the classification of systemic lupus erythematosus.

Authors:  E M Tan; A S Cohen; J F Fries; A T Masi; D J McShane; N F Rothfield; J G Schaller; N Talal; R J Winchester
Journal:  Arthritis Rheum       Date:  1982-11

7.  Stress proteins are immune targets in leprosy and tuberculosis.

Authors:  D Young; R Lathigra; R Hendrix; D Sweetser; R A Young
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

8.  A major immunogen in Schistosoma mansoni infections is homologous to the heat-shock protein Hsp70.

Authors:  R Hedstrom; J Culpepper; R A Harrison; N Agabian; G Newport
Journal:  J Exp Med       Date:  1987-05-01       Impact factor: 14.307

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Authors:  M J Schlesinger
Journal:  J Cell Biol       Date:  1986-08       Impact factor: 10.539

10.  Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen.

Authors:  G Rhodes; H Rumpold; P Kurki; K M Patrick; D A Carson; J H Vaughan
Journal:  J Exp Med       Date:  1987-04-01       Impact factor: 14.307
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  43 in total

1.  Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis.

Authors:  G Hayem; M De Bandt; E Palazzo; S Roux; B Combe; J F Eliaou; J Sany; M F Kahn; O Meyer
Journal:  Ann Rheum Dis       Date:  1999-05       Impact factor: 19.103

2.  Prevention of adjuvant arthritis in rats by a nonapeptide from the 65-kD mycobacterial heat shock protein: specificity and mechanism.

Authors:  X D Yang; J Gasser; U Feige
Journal:  Clin Exp Immunol       Date:  1992-01       Impact factor: 4.330

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Authors:  D B Young
Journal:  Antonie Van Leeuwenhoek       Date:  1990-10       Impact factor: 2.271

Review 4.  Stress proteins and initiation of immune response: chaperokine activity of hsp72.

Authors:  Alexzander Asea
Journal:  Exerc Immunol Rev       Date:  2005       Impact factor: 6.308

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Authors:  M Harboe; A J Quayle
Journal:  Clin Exp Immunol       Date:  1991-10       Impact factor: 4.330

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Authors:  N P Hurst
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

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Authors:  V R Winrow; L McLean; C J Morris; D R Blake
Journal:  Ann Rheum Dis       Date:  1990-02       Impact factor: 19.103

Review 8.  Heat-shock proteins: a missing link in the host-parasite relationship?

Authors:  S H Kaufmann
Journal:  Med Microbiol Immunol       Date:  1990       Impact factor: 3.402

9.  Subcellular localization and chaperone activities of Borrelia burgdorferi Hsp60 and Hsp70.

Authors:  A Scopio; P Johnson; A Laquerre; D R Nelson
Journal:  J Bacteriol       Date:  1994-11       Impact factor: 3.490

10.  Biological autoimmunity screening in hepatitis C patients by anti-HepG2 lysate and anti-heat shock protein 70.1 autoantibodies.

Authors:  B F F Chumpitazi; L Bouillet; M-T Drouet; L Kuhn; J Garin; J-P Zarski; C Drouet
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-08-12       Impact factor: 3.267
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