| Literature DB >> 31714081 |
Maksym Bugera1,2, Serhii Trofymchuk1,3, Karen Tarasenko1,2, Olga Zaporozhets4, Yurii Pustovit1,3, Pavel K Mykhailiuk1,4.
Abstract
A practical method for the synthesis of functionalized aliphatic trifluoromethyl-substituted derivatives from aliphatic acids is developed. The transformation proceeds with sulfur tetrafluoride in the presence of water as a key additive. Compared to previous methods, the reaction gives products with full retention of stereo- and absolute configuration of chiral centers.Entities:
Year: 2019 PMID： 31714081 DOI： 10.1021/acs.joc.9b02596
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354