Literature DB >> 3171336

Range of toxicity of topical cysteamine in rabbit eyes.

S Jain1, T Kuwabara, W A Gahl, M I Kaiser-Kupfer.   

Abstract

Cysteamine eye drops in concentrations from 0.1% to 10% were tested in albino rabbits in both short and long-term experiments. Toxicity, consisting of an inflammatory response, was proportional to the cysteamine concentration and absent at concentrations at or below 0.5%.

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Year:  1988        PMID: 3171336     DOI: 10.1089/jop.1988.4.127

Source DB:  PubMed          Journal:  J Ocul Pharmacol        ISSN: 8756-3320


  2 in total

1.  Clearance of corneal crystals in nephropathic cystinosis by topical cysteamine 0.5%.

Authors:  N P Jones; R J Postlethwaite; J L Noble
Journal:  Br J Ophthalmol       Date:  1991-05       Impact factor: 4.638

2.  Quantitative in vivo and ex vivo confocal microscopy analysis of corneal cystine crystals in the Ctns knockout mouse.

Authors:  Jennifer Simpson; Chyong Jy Nien; Kevin Flynn; Brian Jester; Stephanie Cherqui; James Jester
Journal:  Mol Vis       Date:  2011-08-17       Impact factor: 2.367

  2 in total

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