Xue Feng1, Wei Sun2, Guthrie S Birkhead3, Xuanzhuo Wang1, Zhongmin Guo4, Jiahai Lu5. 1. Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China. 2. Guangzhou Baiyun Airport Customs District People's Republic of China, Guangzhou, Guangdong Province, China. 3. Department of Epidemiology and Biostatistics, School of Public Health, University at Albany, Albany, NY, USA. 4. Experimental Animal Center, Sun Yat-sen University, Guangzhou, Guangdong Province, China. 5. Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China; Key Laboratory for Tropical Diseases Control of Ministry of Education, Sun Yat-sen University, Guangzhou, Guangdong Province, China; One Health Research Centre, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong Province, China. Electronic address: lujiahai@mail.sysu.edu.cn.
Abstract
BACKGROUND: Little comprehensive analysis combining epidemiological and clinical data has been done with mosquito-borne diseases imported into Guangzhou by air travelers. METHODS: We screened international travelers (body temperature >36.5 °C) arriving at Guangzhou Baiyun International Airport, and recorded their epidemiological and clinical information. Whole-blood samples were collected for laboratory diagnosis of dengue virus (DENV), chikungunya virus (CHIKV), zika virus (ZIKV) infections and malaria. RESULTS: Between March 1, 2016 and December 31, 2017, 155 (6.6%) cases (100 of DENV, 21 of CHIKV, 1 of ZIKV, 34 of malaria, including one co-infection of DENV and CHIKV) were identified among 2350 febrile travelers. DENV (90.0%) and CHIKV (100.0%) cases mainly came from Southern and Southeast Asia. Malaria cases (91.2%) mainly came from sub-Saharan Africa. Traveling abroad (28/74, 37.8%) and living/working abroad (11/22, 50.0%) were the most common causes of DENV infection and malaria for Chinese, respectively. Cases with these four mosquito-borne diseases were more likely to have nervous, musculoskeletal and skin symptoms and signs than other febrile diseases (P < 0.001). CONCLUSIONS: It is important to strengthen the surveillance of mosquito-borne diseases among tourists and workers returning from Southeast Asia, Southern Asia and sub-Saharan Africa, especially those with nervous, musculoskeletal and skin symptoms and signs.
BACKGROUND: Little comprehensive analysis combining epidemiological and clinical data has been done with mosquito-borne diseases imported into Guangzhou by air travelers. METHODS: We screened international travelers (body temperature >36.5 °C) arriving at Guangzhou Baiyun International Airport, and recorded their epidemiological and clinical information. Whole-blood samples were collected for laboratory diagnosis of dengue virus (DENV), chikungunya virus (CHIKV), zika virus (ZIKV) infections and malaria. RESULTS: Between March 1, 2016 and December 31, 2017, 155 (6.6%) cases (100 of DENV, 21 of CHIKV, 1 of ZIKV, 34 of malaria, including one co-infection of DENV and CHIKV) were identified among 2350 febrile travelers. DENV (90.0%) and CHIKV (100.0%) cases mainly came from Southern and Southeast Asia. Malaria cases (91.2%) mainly came from sub-Saharan Africa. Traveling abroad (28/74, 37.8%) and living/working abroad (11/22, 50.0%) were the most common causes of DENVinfection and malaria for Chinese, respectively. Cases with these four mosquito-borne diseases were more likely to have nervous, musculoskeletal and skin symptoms and signs than other febrile diseases (P < 0.001). CONCLUSIONS: It is important to strengthen the surveillance of mosquito-borne diseases among tourists and workers returning from Southeast Asia, Southern Asia and sub-Saharan Africa, especially those with nervous, musculoskeletal and skin symptoms and signs.
Authors: Karin Bakran-Lebl; Jeremy V Camp; Jolanta Kolodziejek; Pia Weidinger; Peter Hufnagl; Adriana Cabal Rosel; Andreas Zwickelstorfer; Franz Allerberger; Norbert Nowotny Journal: Transbound Emerg Dis Date: 2021-07-08 Impact factor: 4.521